Browsing by Author "Sukumaran, Vijayakumar"
Now showing items 1-7 of 7
-
Direct Measurement of Vessel Pressure in Chicken Embryo during Development
( Qatar University Press , 2021 , Poster)Hemodynamic conditions play a critical role in embryonic cardiovascular development, and altered blood flow leads to congenital heart defects (CHD). Chicken embryos are commonly used as models of cardiac development, with ... -
Do changes in ace-2 expression affect sars-cov-2 virulence and related complications: A closer look into membrane-bound and soluble forms
( MDPI , 2021 , Article Review)The SARS-CoV-2 virus utilizes angiotensin converting enzyme (ACE-2) for cell entry and infection. This enzyme has important functions in the renin-angiotensin aldosterone system to preserve cardiovascular function. In ... -
Editorial: Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)
( Frontiers Media S.A. , 2022 , Article)Cardiovascular disease is the leading cause of death worldwide, and diabetes, the most common metabolic syndrome, causes a 2–5 times higher risk for heart disease (1). Specifically, cardiovascular complications in people ... -
Experimental Assessment of Cardiovascular Physiology in the Chick Embryo.
( American Association for Anatomy Journals , 2023 , Article Review)High resolution assessment of cardiac functional parameters is crucial in translational animal research. The chick embryo is a historically well-used in vivo model for cardiovascular research due to its many practical ... -
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet.
( BMC , 2020 , Article)Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates ... -
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system
( Springer , 2021 , Article)Experimental and clinical evidence suggests that diabetic subjects are predisposed to a distinct cardiovascular dysfunction, known as diabetic cardiomyopathy (DCM), which could be an autonomous disease independent of ... -
β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto–Kakizaki rat
( Portland Press Ltd , 2021 , Article)A high salt intake exacerbates insulin resistance, evoking hypertension due to systemic perivascular inflammation, oxidative-nitrosative stress and endothelial dysfunction. Angiotensin-converting enzyme inhibitor (ACEi) ...
