Browsing by Author "Tkac J."
Now showing items 1-17 of 17
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2D MXenes as Perspective Immobilization Platforms for Design of Electrochemical Nanobiosensors
( Wiley-VCH Verlag , 2019 , Article Review)MXenes are a new group of 2D nanomaterials with fascinating properties including high electrical conductivity, hydrophilic nature, easily tunable structure and high surface area. This is why MXene modified interfaces are ... -
A graphene-based glycan biosensor for electrochemical label-free detection of a tumor-associated antibody
( MDPI AG , 2019 , Article)The study describes development of a glycan biosensor for detection of a tumor-associated antibody. The glycan biosensor is built on an electrochemically activated/oxidized graphene screen-printed electrode (GSPE). Oxygen ... -
Advanced antifouling zwitterionic layer based impedimetric HER2 biosensing in human serum: Glycoprofiling as a novel approach for breast cancer diagnostics
( Elsevier B.V. , 2018 , Article)There are two key novel components presented here behind identification of potential novel breast cancer (BCa) diagnostic approach: 1. application of photoimmobilizable zwitterionic hydrogels resisting non-specific protein ... -
Advanced impedimetric biosensor configuration and assay protocol for glycoprofiling of a prostate oncomarker using Au nanoshells with a magnetic core
( Elsevier Ltd , 2019 , Article)In this paper several advances were implemented for glycoprofiling of prostate specific antigen (PSA), what can be applied for better prostate cancer (PCa) diagnostics in the future: 1) application of Au nanoshells with a ... -
Antibodies against aberrant glycans as cancer biomarkers
( Taylor and Francis Ltd , 2019 , Article Review)Introduction: The review provides a comprehensive overview about applicability of serological detection of autoantibodies against aberrant glycans as cancer biomarkers. Areas covered: Clinical usefulness of autoantibodies ... -
Electrochemical Impedance Spectroscopy Based Biosensors: Mechanistic Principles, Analytical Examples and Challenges towards Commercialization for Assays of Protein Cancer Biomarkers
( Wiley-VCH Verlag , 2019 , Article Review)Impedimetric affinity biosensors are, without any doubt, among the most sensitive analytical devices available, offering low limits of detection and wide linear response ranges. There are, however, only a few papers detailing ... -
Glycan analysis as biomarkers for testicular cancer
( MDPI AG , 2019 , Article Review)The U.S. Preventive Services Task Force does not recommend routine screening for testicular cancer (TC) in asymptomatic men, essentially because serological testicular cancer (TC) biomarkers are not reliable. The main ... -
Glycomics meets artificial intelligence – Potential of glycan analysis for identification of seropositive and seronegative rheumatoid arthritis patients revealed
( Elsevier B.V. , 2018 , Article)In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on ... -
Graphene oxide-based electrochemical label-free detection of glycoproteins down to aM level using a lectin biosensor
( Royal Society of Chemistry , 2016 , Article)A label-free ultrasensitive impedimetric biosensor with lectin immobilised on graphene oxide (GO) for the detection of glycoproteins from 1 aM is shown here. This is the first time a functional lectin biosensor with lectin ... -
Identification of Molecular Fluorophore as a Component of Carbon Dots able to Induce Gelation in a Fluorescent Multivalent-Metal-Ion-Free Alginate Hydrogel
( Nature Publishing Group , 2019 , Article)We introduce a simple approach to fabricate fluorescent multivalent metal ion-free alginate hydrogels, which can be produced using carbon dots accessible from natural sources (citric acid and L-cysteine). Molecular fluorophore ... -
Modulation of wettability, gradient and adhesion on self-assembled monolayer by counterion exchange and pH
( Academic Press Inc. , 2018 , Article)In this study, two quaternary ammonium salts derived from L-lipoic acid were applied for self-assembled monolayers formation on rough structured gold surface. The derivatives differ in functionality since one possesses ... -
Nanoscale-controlled architecture for the development of ultrasensitive lectin biosensors applicable in glycomics
( Royal Society of Chemistry , 2014 , Article)In this mini-review the most advanced patterning protocols and transducing schemes for the development of ultrasensitive label-free and label-based lectin biosensors for the glycoprofiling of disease markers and some ... -
Polyzwitterionic Hydrogels in Engines Based on the Antipolyelectrolyte Effect and Driven by the Salinity Gradient
( American Chemical Society , 2019 , Article)In this paper, we propose and investigate an original approach to energy conversion based on polyzwitterionic hydrogels, which exhibit an antipolyelectrolyte effect that enables them to swell in salt water and shrink in ... -
Prostate-specific antigen glycoprofiling as diagnostic and prognostic biomarker of prostate cancer
( Royal Society Publishing , 2019 , Article Review)The initial part of this review details the controversy behind the use of a serological level of prostate-specific antigen (PSA) for the diagnostics of prostate cancer (PCa). Novel biomarkers are in demand for PCa diagnostics, ... -
Sensitive detection and glycoprofiling of a prostate specific antigen using impedimetric assays
( Royal Society of Chemistry , 2016 , Article)This study presents a proof-of-concept for the development of an impedimetric biosensor for ultra-sensitive glycoprofiling of prostate specific antigen (PSA). The biosensor exhibits three unique characteristics: (1) analysis ... -
Sulfobetaines Meet Carboxybetaines: Modulation of Thermo- and Ion-Responsivity, Water Structure, Mechanical Properties, and Cell Adhesion
( American Chemical Society , 2019 , Article)A procedure for the preparation of copolymers bearing sulfobetaine and carboxybetaine methacrylic-based monomers by free-radical polymerization is described and discussed. A combination of monomers affects the upper critical ... -
Ti3C2Tx mxene-based light-responsive hydrogel composite for bendable bilayer photoactuator
( MDPI AG , 2020 , Article)Soft actuators based on hydrogel materials, which can convert light energy directly into mechanical energy, are of the utmost importance, especially with enhancements in device development. However, the hunt for specific ...
