Browsing by Author "Achkar, Iman W"
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Anticancer potential of sanguinarine for various human malignancies
Achkar, Iman W; Mraiche, Fatima; Mohammad, Ramzi M; Uddin, Shahab ( Future Medicine Ltd. , 2017 , Article Review)Sanguinarine (Sang) - a benzophenanthridine alkaloid extracted from Sanguinaria canadensis - exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory activities on tumor cells of various cancer types as ... -
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling.
Akhtar, Sabah; Achkar, Iman W; Siveen, Kodappully S; Kuttikrishnan, Shilpa; Prabhu, Kirti S; Khan, Abdul Q; Ahmed, Eiman I; Sahir, Fairooz; Jerobin, Jayakumar; Raza, Afsheen; Merhi, Maysaloun; Elsabah, Hesham M; Taha, Ruba; Omri, Halima El; Zayed, Hatem; Dermime, Said; Steinhoff, Martin; Uddin, Shahab... more authors ... less authors ( Frontiers Media , 2019 , Article)Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a ... -
Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk.
Bhat, Ajaz A; Uppada, Srijayaprakash; Achkar, Iman W; Hashem, Sheema; Yadav, Santosh K; Shanmugakonar, Muralitharan; Al-Naemi, Hamda A; Haris, Mohammad; Uddin, Shahab... more authors ... less authors ( Frontiers Media , 2019 , Article)The ability of epithelial cells to organize through cell-cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions ...