• The burden of bacterial antimicrobial resistance in the WHO Eastern Mediterranean Region 1990–2021: a cross-country systematic analysis with forecasts to 2050 

      Mestrovic, Tomislav; Naghavi, Mohsen; Robles Aguilar, Gisela; Davis Weaver, Nicole; Swetschinski, Lucien R; ... more authors ( Elsevier , 2025 , Article)
      BackgroundAntimicrobial resistance (AMR) is an urgent global crisis and one of the world's most complex challenges. Although there is increasing evidence of its impact on human mortality and morbidity, precise burden ...
    • Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 

      Stein Emil, Vollset; Ababneh, Hazim S; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ...
    • Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019. 

      Harvey, James D; Henrikson, Hannah Jacqueline; Lu, Dan; Pennini, Alyssa; Xu, Rixing; ... more authors ( American Medical Association , 2021 , Article)
      The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. ...
    • Five insights from the Global Burden of Disease Study 2019 

      Christopher J L, Murray; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; ... more authors ( Elsevier , 2020 , Article Review)
      The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ...
    • Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021 

      Dana, Bryazka; Reitsma, Marissa B; Abate, Yohannes Habtegiorgis; Abd Al Magied, Abdallah H A; Abdelkader, Atef; ... more authors ( Elsevier , 2024 , Article)
      BackgroundSmoking is the leading behavioural risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking ...
    • Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019 

      Haidong, Wang; Abbas, Kaja M; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; Abbastabar, Hedayat; ... more authors ( Elsevier , 2020 , Article)
      Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, ...
    • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Michael, Brauer; Roth, Gregory A; Aravkin, Aleksandr Y; Zheng, Peng; Abate, Kalkidan Hassen; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to ...
    • Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 

      Mohsen, Naghavi; Kyu, Hmwe Hmwe; A, Bhoomadevi; Aalipour, Mohammad Amin; Aalruz, Hasan; ... more authors ( Elsevier , 2025 , Article)
      BackgroundTimely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global Burden of Diseases, ...
    • The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019 

      Elysia M, Alvarez; Force, Lisa M; Xu, Rixing; Compton, Kelly; Lu, Dan; ... more authors ( Elsevier , 2022 , Article)
      BackgroundIn estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. ...
    • The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 

      Khanh Bao, Tran; Lang, Justin J; Compton, Kelly; Xu, Rixing; Acheson, Alistair R; ... more authors ( Elsevier , 2022 , Article)
      BackgroundUnderstanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global ...
    • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 

      Natalia V, Bhattacharjee; Schumacher, Austin E; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      Background Accurate assessments of current and future fertility—including overall trends and changing population age structures across countries and regions—are essential to help plan for the profound social, economic, ...
    • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Alize J, Ferrari; Santomauro, Damian Francesco; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2024 , Article)
      Background Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...
    • Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021 

      Hmwe Hmwe, Kyu; Vongpradith, Avina; Dominguez, Regina-Mae Villanueva; Ma, Jianing; Albertson, Samuel B; ... more authors ( Elsevier , 2024 , Article)
      BackgroundDiarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age ...
    • Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023 

      Patrick B, Mark; Stafford, Lauryn K; Grams, Morgan E; Aalruz, Hasan; Abd ElHafeez, Samar; ... more authors ( Elsevier , 2025 , Article)
      BackgroundChronic kidney disease (CKD) is common and ranks among the leading causes of mortality and morbidity. This analysis aimed to present global CKD estimates using the Global Burden of Diseases, Injuries, and Risk ...
    • Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 

      Kanyin Liane, Ong; Stafford, Lauryn K; McLaughlin, Susan A; Boyko, Edward J; Vollset, Stein Emil; ... more authors ( Elsevier , 2023 , Article)
      BackgroundDiabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global ...
    • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Jaimie D, Steinmetz; Seeher, Katrin Maria; Schiess, Nicoline; Nichols, Emma; Cao, Bochen; ... more authors ( Elsevier , 2024 , Article)
      Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous ...
    • Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021. 

      Rautalin, Ilari; Volovici, Victor; Stark, Benjamin A; Johnson, Catherine O; Kaprio, Jaakko; ... more authors ( American Medical Association , 2025 , Article)
      Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments. Nevertheless, epidemiological studies often cluster SAH with other ...
    • Global, regional, and national prevalence of kidney failure with replacement therapy and associated aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 

      Rafferty, Quinn; Stafford, Lauryn K; Vos, Theo; Thomé, Fernando Saldanha; Aalruz, Hasan; ... more authors ( Elsevier , 2025 , Article)
      Background: Kidney failure with replacement therapy (KFRT) such as dialysis or transplantation represents a severe stage of chronic kidney disease (CKD) and poses a major global health burden. Although many CKD cases are ...
    • In silico design of multi-epitope vaccines against the hantaviruses by integrated structural vaccinology and molecular modeling approaches 

      Ali, Liaqat; Rauf, Sobiah; Khan, Abbas; Rasool, Samreen; Raza, Rabail Zehra; ... more authors ( Public Library of Science , 2024 , Article)
      Hantaviruses are single-stranded RNA viruses belonging to the family Bunyaviridae that causes hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS) worldwide. Currently, there is no ...
    • Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 

      Rafael, Lozano; Fullman, Nancy; Mumford, John Everett; Knight, Megan; Barthelemy, Celine M; ... more authors ( Elsevier , 2020 , Article)
      Background Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority ...