Browsing by Author "Bertok, T."
Now showing items 1-9 of 9
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2D MXenes as Perspective Immobilization Platforms for Design of Electrochemical Nanobiosensors
Lorencova L.; Gajdosova V.; Hroncekova S.; Bertok T.; Blahutova J.; Vikartovska A.; Parrakova L.; Gemeiner P.; Kasak P.; Tkac J.... more authors ... less authors ( Wiley-VCH Verlag , 2019 , Article Review)MXenes are a new group of 2D nanomaterials with fascinating properties including high electrical conductivity, hydrophilic nature, easily tunable structure and high surface area. This is why MXene modified interfaces are ... -
Advanced antifouling zwitterionic layer based impedimetric HER2 biosensing in human serum: Glycoprofiling as a novel approach for breast cancer diagnostics
Chocholova E.; Bertok T.; Lorencova L.; Holazova A.; Farkas P.; Vikartovska A.; Bella V.; Velicova D.; Kasak P.; Eckstein A.A.; Mosnacek J.; Hasko D.; Tkac J.... more authors ... less authors ( Elsevier B.V. , 2018 , Article)There are two key novel components presented here behind identification of potential novel breast cancer (BCa) diagnostic approach: 1. application of photoimmobilizable zwitterionic hydrogels resisting non-specific protein ... -
Advanced impedimetric biosensor configuration and assay protocol for glycoprofiling of a prostate oncomarker using Au nanoshells with a magnetic core
Bertok T.; Lorencova L.; Hroncekova S.; Gajdosova V.; Jane E.; Hires M.; Kasak P.; Kaman O.; Sokol R.; Bella V.; Eckstein A.A.; Mosnacek J.; Vikartovska A.; Tkac J.... more authors ... less authors ( Elsevier Ltd , 2019 , Article)In this paper several advances were implemented for glycoprofiling of prostate specific antigen (PSA), what can be applied for better prostate cancer (PCa) diagnostics in the future: 1) application of Au nanoshells with a ... -
Electrochemical Impedance Spectroscopy Based Biosensors: Mechanistic Principles, Analytical Examples and Challenges towards Commercialization for Assays of Protein Cancer Biomarkers
Bertok T.; Lorencova L.; Chocholova E.; Jane E.; Vikartovska A.; Kasak P.; Tkac J.... more authors ... less authors ( Wiley-VCH Verlag , 2019 , Article Review)Impedimetric affinity biosensors are, without any doubt, among the most sensitive analytical devices available, offering low limits of detection and wide linear response ranges. There are, however, only a few papers detailing ... -
Glycomics meets artificial intelligence – Potential of glycan analysis for identification of seropositive and seronegative rheumatoid arthritis patients revealed
Chocholova E.; Bertok T.; Jane E.; Lorencova L.; Holazova A.; Belicka L.; Belicky S.; Mislovicova D.; Vikartovska A.; Imrich R.; Kasak P.; Tkac J.... more authors ... less authors ( Elsevier B.V. , 2018 , Article)In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on ... -
Modulation of wettability, gradient and adhesion on self-assembled monolayer by counterion exchange and pH
Mosn??ek J.; Popelka A.; Osicka J.; Filip J.; Ilcikova M.; Kollar J.; Yousaf A.B.; Bertok T.; Tkac J.; Kasak P.... more authors ... less authors ( Academic Press Inc. , 2018 , Article)In this study, two quaternary ammonium salts derived from L-lipoic acid were applied for self-assembled monolayers formation on rough structured gold surface. The derivatives differ in functionality since one possesses ... -
Nanoscale-controlled architecture for the development of ultrasensitive lectin biosensors applicable in glycomics
Klukova, L.; Bertok, T.; Kasak, P.; Tkac, J. ( Royal Society of Chemistry , 2014 , Article)In this mini-review the most advanced patterning protocols and transducing schemes for the development of ultrasensitive label-free and label-based lectin biosensors for the glycoprofiling of disease markers and some ... -
Prostate-specific antigen glycoprofiling as diagnostic and prognostic biomarker of prostate cancer
Tkac J.; Gajdosova V.; Hroncekova S.; Bertok T.; Hires M.; Jane E.; Lorencova L.; Kasak P.... more authors ... less authors ( Royal Society Publishing , 2019 , Article Review)The initial part of this review details the controversy behind the use of a serological level of prostate-specific antigen (PSA) for the diagnostics of prostate cancer (PCa). Novel biomarkers are in demand for PCa diagnostics, ... -
Sensitive detection and glycoprofiling of a prostate specific antigen using impedimetric assays
Pihíková, D.; Belicky, Š.; Kasák, P.; Bertok, T.; Tkac, J. ( Royal Society of Chemistry , 2016 , Article)This study presents a proof-of-concept for the development of an impedimetric biosensor for ultra-sensitive glycoprofiling of prostate specific antigen (PSA). The biosensor exhibits three unique characteristics: (1) analysis ...