Browsing by Author "Yalcin, Huseyin"

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Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model

Yalcin, Huseyin; Da'As, Sahar; Mohammed, Iman; Nasrallah, Gheyath; Al Suwaidi, Jasim; Yacoub, Magdi... more authors ... less authors ( Qscience. , 2016 , Conference)
Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ...
THE ROLE OF P90 RIBOSOMAL S6 KINASE AND AUTOPHAGY IN SUNITINIB AND PONATINIB-INDUCED CARDIOTOXICITY

SULEIMAN, MUNA (2019 , Master Thesis)
In recent years, the paradigm cancer management has shifted towards a targeted approach. Among the newly targeted anticancer therapies are ponatinib and sunitinib, small molecules tyrosine kinase inhibitors (TKIs), used ...