Browsing by Author "Sahebkar, Amirhossein"

Now showing items 1-20 of 50

    • Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis 

      Jamialahamdi, Tannaz; Eid, Ali H.; Nguyen, Ninh T.; Gadde, Kishore M.; Sukhorukov, Vasily N.; ... more authors (2024 , Article)
      CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review ...

    • Beyond fat: Does semaglutide affect lean mass? 

      Tannaz, Jamialahmadi; Eid, Ali H.; Gadde, Kishore M.; Almahmeed, Wael; Kroh, Matthew; ... more authors ( Elsevier , 2025 , Article)
      This opinion paper aims to discuss the influence of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), on lean mass beyond its impact on weight loss. Although significant weight loss is achieved with ...

    • Biochemical and cellular basis of oxidative stress: Implications for disease onset 

      Aramouni, Karl; Assaf, Roland; Shaito, Abdullah; Fardoun, Manal; Al-Asmakh, Maha; ... more authors ( Wiley , 2023 , Article Review)
      Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ...

    • Bridging conventional medicine and traditional, complementary, and alternative approaches: Fostering collaborative attempts for a holistic healthcare system 

      Eid, Ali H.; Sahebkar, Amirhossein ( Elsevier , 2023 , Article)
      Dear Editor, We read the paper entitled “The future of integrative health: vision, values, and principles for positive, sustainable systemic change” by Kemper, which was published last month.1 The points discussed therein ...

    • Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 

      Stein Emil, Vollset; Ababneh, Hazim S; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ...

    • C-peptide in diabetes: A player in a dual hormone disorder? 

      Dakroub, Ali; Dbouk, Ali; Asfour, Aref; Nasser, Suzanne A.; El-Yazbi, Ahmed F.; ... more authors ( Wiley-Blackwell , 2024 , Article)
      C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ...

    • Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats 

      Hosseini, Azar; Safari, Mohammad Kazem; Rajabian, Arezoo; Boroumand-Noughabi, Samaneh; Eid, Ali H.; ... more authors ( Frontiers Media S.A. , 2022 , Article)
      Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum ...

    • Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats 

      Hosseini, Azar; Ghorbani, Atieh; Alavi, Mohaddeseh Sadat; Forouhi, Nima; Rajabian, Arezoo; ... more authors ( Frontiers Media SA , 2023 , Article)
      Introduction: Oxidative stress is a major instigator of various cardiovascular diseases, including myocardial infarction (MI). Despite available drugs, there is still an increased need to look for alternative therapies or ...

    • Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery 

      Jangjoo, Sara; Emami, Nima; Sahranavard, Mehrdad; Shah, Najeeb Z.; Alidadi, Mona; ... more authors ( Springer , 2023 , Article)
      Purpose: This study aimed to ascertain the diagnostic accuracy of non-invasive liver function tests in liver fibrosis and assess their changes after metabolic surgery. Materials and Methods: 1005 individuals with severe ...

    • The differential expression of adipose tissue genes in short, medium and long-term periods after bariatric surgery 

      Mahjoubin-Tehran, Maryam; Atkin, Stephen L.; Jamialahmadi, Tannaz; Kroh, Matthew; Eid, Ali H.; ... more authors ( Springer Nature , 2024 , Article)
      Bariatric surgery is an approved treatment for obesity that consistently improves metabolic syndrome, with well-documented beneficial effects on dyslipidemia, cardiovascular risk, nonalcoholic fatty liver disease and glucose ...

    • Drug-use disorders in the Eastern Mediterranean Region: a glance at GBD 2019 findings 

      Amirkafi, Ali; Mohammadi, Faezeh; Tehrani-Banihashemi, Arash; Abbasi-Kangevari, Mohsen; Abbasi-Kangevari, Zeinab; ... more authors ( Springer , 2023 , Article)
      Purpose: The aim of this study is to investigate drug use disorders which are a major cause of Disability Adjusted Life Years (DALYs) in the Eastern Mediterranean Region (EMR). Methods: This article is a part of the global ...

    • Drugs from the ocean floor 

      Maha, Khachab; Sahebkar, Amirhossein; Eid, Ali H. ( Elsevier , 2025 , Other)
      The past decades have demonstrated the pharmaceutical, nutraceutical, and market potentials of bioactive compounds extracted from marine organisms. These marine bioactive compounds possess unique chemical structures and ...

    • Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis 

      Jamialahmadi, Tannaz; Reiner, Željko; Alidadi, Mona; Almahmeed, Wael; Kesharwani, Prashant; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Background: Obesity, and in particular extreme obesity, as a global health problem is an important risk factor for many diseases, including atherosclerotic cardiovascular disease (ACVD). Bariatric surgery might stop or ...

    • The Effect of Bariatric Surgery on PAI-1 Levels: A Systematic Review and Meta-analysis 

      Jamialahamdi, Tannaz; Mirhadi, Elaheh; Almahmeed, Wael; Sukhorukov, Vasily N.; Eid, Ali H.; ... more authors ( Springer Nature , 2024 , Article)
      The purpose of this meta-analysis was to determine the effect of bariatric surgery on circulating PAI-1. The meta-analysis was provided by comprehensive meta-analysis (CMA) V4 software. Meta-analysis of 33 studies showed ...

    • Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis 

      Jamialahamdi, Tannaz; Mirhadi, Elaheh; Atkin, Stephen L.; le Roux, Carel W.; Kroh, Matthew; ... more authors ( springer link , 2023 , Article)
      Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and ...

    • The effect of nuts consumption on circulating oxidized low-density lipoproteins: A systematic review and meta-analysis of randomized controlled trials. 

      Abbasifard, Mitra; Jamialahmadi, Tannaz; Reiner, Željko; Eid, Ali H; Sahebkar, Amirhossein ( Wiley , 2023 , Article Review)
      This systematic review and meta-analysis evaluated the effect of nuts in decreasing circulating levels of oxidized low-density lipoproteins (ox-LDL). A literature search was performed of major electronic databases ...

    • Effect of statins on abdominal aortic aneurysm 

      Azar, Hosseini; Sahranavard, Toktam; Reiner, Željko; Jamialahmadi, Tannaz; Dhaheri, Yusra Al; ... more authors ( Elsevier , 2022 , Article Review)
      Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ...

    • The Effects of Statin Treatment on Serum Ferritin Levels: A Systematic Review and Meta-Analysis 

      Jamialahmadi, Tannaz; Abbasifard, Mitra; Reiner, Željko; Rizzo, Manfredi; Eid, Ali H.; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Background: Statins are the most widely used drugs for decreasing elevated serum LDL-cholesterol (LDL-C) and thus for the prevention of atherosclerotic cardiovascular disease (ASCVD), but they have also some pleiotropic ...

    • Effects of Trehalose Administration in Patients with Mucopolysaccharidosis Type III 

      Mobini, Moein; Radbakhsh, Shabnam; Kubaski, Francyne; Eshraghi, Peyman; Vakili, Saba; ... more authors ( Bentham Science Publishers , 2023 , Article)
      Background and Aim: Mucopolysaccharidosis type III (MPS III) is a rare autosomal recessive lysosomal storage disease (LSD) caused by a deficiency of lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs), ...

    • Effects of Trehalose Administration in Patients with Mucopolysaccharidosis Type III. 

      Mobini, Moein; Radbakhsh, Shabnam; Kubaski, Francyne; Eshraghi, Peyman; Vakili, Saba; ... more authors ( Europe PMC , 2023 , Article)
      Mucopolysaccharidosis type III (MPS III) is a rare autosomal recessive lysosomal storage disease (LSD) caused by a deficiency of lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs), mainly in the ...