Browsing by Author "Abdesselem, Houari B."
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Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study
Mesleh, Areej; Ehtewish, Hanan; de la Fuente, Alberto; Al-shamari, Hawra; Ghazal, Iman; Al-Faraj, Fatema; Al-Shaban, Fouad; Abdesselem, Houari B.; Emara, Mohamed; Alajez, Nehad M.; Arredouani, Abdelilah; Decock, Julie; Albagha, Omar; Stanton, Lawrence W.; Abdulla, Sara A.; El-Agnaf, Omar M.A.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Autism spectrum disorder (ASD) is an umbrella term that encompasses several disabling neurodevelopmental conditions. These conditions are characterized by impaired manifestation in social and communication skills with ... -
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Gupta, Vijay; Salim, Safa; Hmila, Issam; Vaikath, Nishant N.; Sudhakaran, Indulekha P.; Ghanem, Simona S.; Majbour, Nour K.; Abdulla, Sara A.; Emara, Mohamed M.; Abdesselem, Houari B.; Lukacsovich, Tamas; Erskine, Daniel; El-Agnaf, Omar M.A.... more authors ... less authors ( Springer Nature , 2020 , Article)Synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are characterized by pathological accumulation of α-synuclein (α-syn). Amongst the various approaches ... -
High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder
Mesleh, Areej; Ehtewish, Hanan; Lennard, Katie; Abdesselem, Houari B.; Al-Shaban, Fouad; Decock, Julie; Alajez, Nehad M.; Arredouani, Abdelilah; Emara, Mohamed M.; Albagha, Omar; Stanton, Lawrence W.; Abdulla, Sara A.; Blackburnand, Jonathan M.; El-Agnaf, Omar M.A.... more authors ... less authors ( Frontiers Media SA , 2023 , Article)Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by defects in two core domains, social/communication skills and restricted/repetitive behaviors or interests. There is no approved ... -
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
Mir, Fayaz Ahmad; Abdesselem, Houari B.; Cyprian, Farhan; Iskandarani, Ahmad; Doudin, Asmma; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ...