تصفح حسب المؤلف "n 2012220881"
السجلات المعروضة 1 -- 19 من 19
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A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
( Elsevier B.V. , 2016 , Article)Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ... -
Advances in nasal drug delivery systems
( Academic Press , 2020 , Book chapter)Nasal drug delivery has been around for centuries and employed both leisure and recreations and also for the treatment of various conditions such as migraine, decongestion, sinusitis, rhinitis, and in emergency. The route ... -
Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis
( Elsevier , 2023 , Article)Oral aphthous stomatitis is a common disorder treated with the immunomodulatory drug Amlexanox (AMX), that was administered as a mucoadhesive paste (Aphthasol®). This product was discontinued by FDA in 2014 due to the ... -
Carbon nanotubes drug delivery system for cancer treatment
( Academic Press , 2020 , Book chapter)There has been a predominant interest in using nanotechnology for drug delivery applications, especially for cite-specific targeting. Recently, interest in the potential of carbon nanotubes (CNT) to deliver bio-molecules ... -
Carbon nanotubes: Applications in cancer therapy and drug delivery research
( Elsevier , 2018 , Book chapter)Carbon nanotubes (CNTs) are novel nanocarrier systems that have a wide range of applications in science, engineering, and, the environment. Owing to the possible functionalization of CNTs (i.e., surface-engineering of the ... -
Characterization of cochleate nanoparticles for delivery of the anti-asthma drug beclomethasone dipropionate
( Academic Press , 2020 , Book chapter)Cochleates are an exciting new class of nanocarriers derived from multilamellar liposomes. They have a “cigerette like” structures in which the phospholipid bilayers are joined together by calcium ion bridges making them ... -
Delivery of anticancer molecules using carbon nanotubes
( Springer International Publishing , 2016 , Book chapter)Since their discovery in 1991, carbon nanotubes (CNTs) have emerged as material structures with numerous potential applications with a number of products already in the market place. An exciting application, which is ... -
Design characteristics of inhaler devices used for pulmonary delivery of medical aerosols
( Springer International Publishing , 2016 , Book chapter)For the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. ... -
Impact of nanosizing on the formation and characteristics of polymethacrylate films: micro- versus nano-suspensions
( Taylor and Francis Ltd. , 2021 , Article)Aqueous-based film coating suspensions are associated with reliance on alkalinising reagents and poor film formation. The impact of particle size in this process and resultant film properties remains unclear. This study ... -
Introduction to nanotechnology
( Elsevier , 2019 , Book chapter)Nanotechnology describes the science and technology related to the control and manipulation of matter and devices on a scale less than 100 nm and involves fields such as applied physics, materials science, chemistry, ... -
Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer.
( Elsevier , 2019 , Article)The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs). Elevated activity of cytochrome P4501A1 (CYP1A1) plays an important role in the metabolic ... -
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
( Elsevier, Ltd , 2016 , Article)The aim of this study is to investigate using nanoemulsion formulations as drug-delivery vehicles of paclitaxel (PX), a poor water-soluble anticancer drug. Two commercially available nanoemulsion fat formulations (Clinoleic ... -
PEGylated graphene oxide for tumor-targeted delivery of paclitaxel
( Future Medicine Ltd. , 2015 , Article)Aim: The graphene oxide (GO) sheet has been considered one of the most promising carbon derivatives in the field of material science for the past few years and has shown excellent tumor-targeting ability, biocompatibility ... -
Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer
( Springer , 2021 , Article)© 2020, The Author(s). Purpose: The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods: Proliposome powders were ... -
Proliposome powders prepared using a slurry method for the generation of beclometasone dipropionate liposomes
( Elsevier , 2015 , Article)A novel “slurry method” was described for the preparation of proliposome powders using soya phosphatidylcholine (SPC) with cholesterol (1:1) and for incorporation of beclometasone dipropionate (BDP) at 2mole% of the total ... -
Proliposomes: A Manufacturing Technology of Liposomes for Pulmonary Drug Delivery
( Springer Nature , 2025 , Book)Proliposome technologies are stable phospholipid formulations that provide an approach to generating liposomes upon addition of aqueous phase prior to administration. In this monograph, the authors review the potential of ... -
Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation
( Taylor & Francis , 2019 , Article)Ropinirole hydrochloride (RH) is an anti-Parkinson drug with relativity low oral bioavailability owing to its extensive hepatic first pass metabolism. Spray-dried mucoadhesive alginate microspheres of RH were developed and ... -
Spray-Dried Proliposome Microparticles for High-Performance Aerosol Delivery Using a Monodose Powder Inhaler
( Springer New York LLC , 2018 , Article)© 2018, American Association of Pharmaceutical Scientists. Proliposome formulations containing salbutamol sulphate (SS) were developed using spray drying, and the effects of carrier type (lactose monohydrate (LMH) or ... -
Taxane anticancer formulations: challenges and achievements
( Academic Press , 2020 , Book chapter)Taxanes represent a prominent anticancer family. Paclitaxel and docetaxel are the most well-known taxanes owing to their activity against many types of cancers. The poor solubility of taxanes in water is a major obstacle ...
