تصفح حسب المؤلف "n 2013204690"
السجلات المعروضة 1 -- 14 من 14
-
A comprehensive production method of self-cryoprotected nano-liposome powders
( Elsevier , 2015 , Article)This study provided a convenient approach for large scale production of hydrogenated soya phosphatidylcholine nano-liposome powders using beclometasone dipropionate as a model drug and sucrose as proliposome carrier. ... -
A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
( Elsevier B.V. , 2016 , Article)Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ... -
Anticancer drug delivery: Investigating the impacts of viscosity on lipid-based formulations for pulmonary targeting
( Elsevier , 2024 , Article)Pulmonary drug delivery via aerosolization is a non-intrusive method for achieving localized and systemic effects. The aim of this study was to establish the impact of viscosity as a novel aspect (i.e., low, medium and ... -
Design characteristics of inhaler devices used for pulmonary delivery of medical aerosols
( Springer International Publishing , 2016 , Book chapter)For the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. ... -
Development and Characterization of Novel Combinations and Compositions of Nanostructured Lipid Carrier Formulations Loaded with Trans-Resveratrol for Pulmonary Drug Delivery
( MDPI , 2024 , Article)Background/Objectives: This study aimed to fabricate, optimize, and characterize nanostructured lipid carriers (NLCs) loaded with trans-resveratrol (TRES) as an anti-cancer drug for pulmonary drug delivery using medical ... -
Enhancing gliclazide solubility using solid dispersions with carboxymethyl chitosan and polyvinylpyrrolidone K30 as polymeric carriers
( Taylor and Francis , 2025 , Article)Background: Gliclazide (Glz) is a second-generation sulfonylurea antidiabetic drug, used to treat type II diabetes mellitus. Glz is a class II drug according to the biopharmaceutic classification system (BCS), indicating ... -
Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers
( Elsevier , 2021 , Article)Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect. Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer protection from degradation and enhance ... -
A Facile and Novel Approach to Manufacture Paclitaxel-Loaded Proliposome Tablet Formulations of Micro or Nano Vesicles for Nebulization
( Springer , 2020 , Article)© 2020, The Author(s). Purpose: The aim of this study was to develop novel paclitaxel-loaded proliposome tablet formulations for pulmonary drug delivery. Method: Proliposome powder formulations (i.e. F1 – F27) were prepared ... -
Impact of dispersion media and carrier type on spray-dried proliposome powder formulations loaded with beclomethasone dipropionate for their pulmonary drug delivery via a next generation impactor
( Public Library of Science , 2023 , Article)Drug delivery via aerosolization for localized and systemic effect is a non-invasive approach to achieving pulmonary targeting. The aim of this study was to prepare spray-dried proliposome (SDP) powder formulations to ... -
Impact of nanosizing on the formation and characteristics of polymethacrylate films: micro- versus nano-suspensions
( Taylor and Francis Ltd. , 2021 , Article)Aqueous-based film coating suspensions are associated with reliance on alkalinising reagents and poor film formation. The impact of particle size in this process and resultant film properties remains unclear. This study ... -
Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer
( Springer , 2021 , Article)© 2020, The Author(s). Purpose: The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods: Proliposome powders were ... -
Proliposome Powders for the Generation of Liposomes: the Influence of Carbohydrate Carrier and Separation Conditions on Crystallinity and Entrapment of a Model Antiasthma Steroid
( Springer New York LLC , 2018 , Article)Formulation effects on the entrapment of beclometasone dipropionate (BDP) in liposomes generated by hydration of proliposomes were studied, using the high-density dispersion medium deuterium oxide in comparison to deionized ... -
Proliposome powders prepared using a slurry method for the generation of beclometasone dipropionate liposomes
( Elsevier , 2015 , Article)A novel “slurry method” was described for the preparation of proliposome powders using soya phosphatidylcholine (SPC) with cholesterol (1:1) and for incorporation of beclometasone dipropionate (BDP) at 2mole% of the total ... -
Proliposomes: A Manufacturing Technology of Liposomes for Pulmonary Drug Delivery
( Springer Nature , 2025 , Book)Proliposome technologies are stable phospholipid formulations that provide an approach to generating liposomes upon addition of aqueous phase prior to administration. In this monograph, the authors review the potential of ...
