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المؤلفAl-Kandari, Halema
المؤلفYounes, Nadin
المؤلفAl-Jamal, Ola
المؤلفZakaria, Zain Z
المؤلفNajjar, Huda
المؤلفAlserr, Farah
المؤلفPintus, Gianfranco
المؤلفAl-Asmakh, Maha A
المؤلفAbdullah, Aboubakr M
المؤلفNasrallah, Gheyath K
تاريخ الإتاحة2019-04-02T10:53:42Z
تاريخ النشر2019-03-01
اسم المنشورNanomaterials
المعرّفhttp://dx.doi.org/10.3390/nano9040488
الاقتباسAl-Kandari, H.; Younes, N.; Al-Jamal, O.; Zakaria, Z.Z.; Najjar, H.; Alserr, F.; Pintus, G.; Al-Asmakh, M.A.; Abdullah, A.M.; Nasrallah, G.K. Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO2 Photocatalytic Nanocomposites Using the Zebrafish Embryo Model. Nanomaterials 2019, 9, 488.
الرقم المعياري الدولي للكتاب2079-4991
معرّف المصادر الموحدhttp://hdl.handle.net/10576/11464
الملخصAdvanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H₂RGOTi)-reduced graphene oxide/TiO₂ semiconductor photocatalysts recently employed in AOPs. For this purpose, acutoxicity, cardiotoxicity, neurobehavioral toxicity, hematopoietic toxicity, and hatching rate were determinate. For the RGOTi, the no observed effect concentration (NOEC, mortality/teratogenicity score <20%) and the median lethal concentration (LC) were <400 and 748.6 mg/L, respectively. H₂RGOTi showed a NOEC similar to RGOTi. However, no significant mortality was detected at all concentrations used in the acutoxicity assay (up to1000 mg/L), thus indicating a hypothetical LC higher than 1000 mg/L. According to the Fish and Wildlife Service Acute Toxicity Rating Scale, RGOTi can be classified as "practically not toxic" and H₂RGOTi as "relatively harmless". However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. Indeed, the aforementioned teratogenic phenotypes were less devastating in H₂RGOTi-treated embryos, suggesting that the hydrogen-reduced graphene oxide/TiO₂ photocatalysts may be more ecofriendly than the thermally-reduced ones.
اللغةen
الناشرMDPI
الموضوعLC50
nanocomposite photocatalysts
reduced graphene oxide/TiO2
toxicity
zebrafish
العنوانEcotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
النوعArticle
رقم العدد4
رقم المجلد9
ESSN2079-4991
dc.accessType Open Access


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