Biomedical Sciences
Recent Submissions
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Halogen-augmented pyrrole bisurea molecular tweezers for corrosion inhibition of Fe(110) surface: A first-principle investigation
( Elsevier , 2025 , Article)Iron rust imposes significant economic and industrial challenges, thus the need for the development of effective and environmentally friendly inhibitors. The research here leverages first-principles density function theory ... -
Seroprevalence of four zoonotic viral diseases in camels in Qatar
( Elsevier , 2025 , Article)BackgroundUnderstanding the dynamics of zoonotic diseases is integral to the One Health approach, as it guides strategies to mitigate the impact of infections on both animal and human health. In Qatar, the circulation of ... -
Evaluating the cost-effectiveness of COVID-19 mRNA primary-series vaccination in Qatar: An integrated epidemiological and economic analysis
( PLoS One , 2025 , Article)Qatar implemented a mass primary-series vaccination campaign to mitigate the impact of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to retrospectively evaluate the cost-effectiveness of this program ... -
Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart.
( Wiley , 2026 , Article Review)Macrophages are a key component of innate immunity and regulate cardiac phenotypes by their polarization state. The classical M1 macrophages are activated by pro-inflammatory stimuli, whereas M2 macrophages are activated ... -
N-Lactoyl amino acids: insights from metabolite genome-wide association studies and phenome-wide association analysis
( Oxford University Press , 2025 , Article)N-lactoyl-amino acids (Lac-AA) are emerging as important metabolites with diverse physiological roles. This study integrates metabolomics and genomics to investigate the genetic determinants and clinical relevance of three ... -
In Vitro Analysis of the Dynamic Role of the Bacterial Virulence Factors in Skin Wound Healing
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)The skin acts as a primary barrier against environmental insults and maintains homeostasis. Injury initiates a wound healing cascade of hemostasis, inflammation, proliferation, and remodeling. In chronic wounds, persistent ... -
Deciphering the genetic diversity in the Arabian Peninsula and Africa: insights from Y-STR data
( Springer Nature , 2025 , Article)Middle Eastern and African populations make up a significant portion of the global population and exhibit substantial genetic diversity. However, genetic studies on these populations have been largely underrepresented ... -
Microsecond simulations to investigate the structural mechanism of super-resistant double mutations in BTK to the covalent inhibitor ibrutinib in multiple leukemia
( Nature Research , 2025 , Article)Bruton’s Tyrosine Kinase (BTK) is an anchor in B-cell receptor signaling and plays an important role in chronic lymphocytic leukemia (CLL). The use of covalent inhibitors of BTK, such as ibrutinib, enhances the survival ... -
Mental health of university students: a cross-sectional study from Qatar
( Nature Research , 2025 , Article)This study explored the prevalence, associated factors, and management strategies related to mental health among university students in Qatar. A cross-sectional survey was conducted among students aged 18 and older. Data ... -
Effectiveness and durability of a fourth dose of ancestral-strain mRNA vaccines against SARS-CoV-2 infection: a nationwide matched cohort study in Qatar
( Nature Research , 2025 , Article)Concerns about waning immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the emergence of new variants underscore the need for booster doses. Using a matched cohort design, this ... -
Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
( Walter de Gruyter GmbH , 2025 , Article Review)Cancer remains one of the most prevalent causes of mortality worldwide and thus necessitates the development of novel therapeutic strategies. Snake venom, consisting of a complex mixture of bioactive proteins and peptides, ... -
Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential
( John Wiley and Sons Inc , 2025 , Article Review)Background: Cancer represents a complex group of diseases characterized by abnormal cell proliferation, invasion, and metastasis. These features pose significant challenges to conventional therapeutic approaches, necessitating ... -
Laboratory-acquired infections in the Middle East and North Africa region: a systematic review of reported cases and biosafety gaps
( Elsevier , 2025 , Article)BackgroundLaboratory-acquired infections (LAIs) are a significant occupational health hazard to laboratory workers, who can become infected by various pathogens handled as part of their work, including bacteria, fungi, ... -
Estimating SARS-CoV-2 infection incidence and detection rates: Demonstrating a novel surveillance method
( Elsevier , 2025 , Article)ObjectivesAssessing the cumulative incidence of infection conventionally relies on documented infections or serological surveys, both of which have limitations. This study introduces a novel and practical method leveraging ... -
The microbiome-lymphoma Axis: A systematic review and Meta-analysis of gut Dysbiosis pattern in diffuse large B-cell lymphoma
( Elsevier , 2025 , Article Review)BackgroundGut microbiota has emerged as a critical mediator of immune homeostasis and cancer biology. Increasing evidence suggests that gut dysbiosis may play a significant role in the pathogenesis of diffuse large B-cell ... -
ATM inhibitors in cancer radiotherapy: Mechanisms, clinical development, and future directions
( Elsevier , 2025 , Article Review)Ataxia-telangiectasia mutated (ATM) kinase plays a pivotal role in the cellular response to DNA damage. Under normal conditions, ATM acts as a tumor suppressor by regulating pathways that lead to apoptosis and cell cycle ... -
Intranasal CD40-targeted recombinant MERS-CoV S1 protein is superior to intramuscular immunization in eliciting systemic and mucosal immune responses in mice
( Elsevier , 2026 , Article)The Middle East respiratory syndrome coronavirus (MERS-CoV) is a global One Health challenge with a potential pandemic threat, with no approved vaccines or antiviral drugs available to date. Thus, there is an urgent need ... -
ANTI-CANCEROUS POTENTIAL OF EXTRACTS OF QATARI PLANTS AGAINST A549 LUNG CANCER CELLS AND IDENTIFICATION OF THEIR BIOACTIVE COMPOUNDS UREP30-002-3-002 (BH - 250026)
( QRDI Council , 2025 , Conference)• Lung cancer is the leading cause of cancer deaths worldwide, with NSCLC accounting for most cases. • In Qatar, incidence is rising, driven by tobacco use and late-stage diagnosis. • Current therapies face major limitations, ... -
Thymol's Nanoencapsulation Reduces its Toxicity in Human Cells and Zebrafish Embryos
( Saudi Pharmacy Association (SPS)- Ministry of Health , 2025 , Conference)Thymol, a monoterpenoid and a major bioactive constituent of essential oils (EOs) derived from the plants of Lamiacea family such as Thyme, garnered wider research interest for its diverse biological activity and industrial ... -
PBA 23: Nanoencapsulation of Thymol Mitigates its Toxicity in Cells and Zebrafish Embryos
( College of Education, Qatar University , 2025 , Conference)Thymol, a monoterpenoid and a major boactive constituent of essential oils (EOs) derived from the plants of Lamiacea species such as Thyme, has garnered wider research interest for its diverse pharmaceutical, food, and ...
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