Evaluating the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression

Abstract

Purpose: This study was aimed to evaluate the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression. Methods: One thousand and fourteen patients attending outpatient diabetes clinic at a hospital in the northern part of Malaysia were retrospectively followed. Data were collected over a period of three years. Data were analysed using SPSS software package version 15.0 (SPSS Inc., Chicago, IL, U.S.A.). Results: Diabetes was more predominant among the Chinese and female patients. Hypertension and dyslipidaemia concurrently was found among 43% of the patients as comorbidity. The majority of the participants didn’t achieve good glycaemic control (92.9%). Patients with two complications had the highest HbA1c level (8.5 ± 2%) (P=0.035). There were no significant differences in the BP and lipid profile between the groups in relation to the number of complications (P>0.05). As the disease duration increases there were a decrease in the number of patients with no complications and an increment in the number of patients with a number of complications. Conclusions: There were significant differences in glycaemic control in relation to the diabetic complications in addition to the obvious differences in the number of complications and comorbidities occurrence as the disease progressed. © 2018, Pharmainfo Publications.