Synthesis and characterization of magnetic nanostructured lipid carriers (mNLCs) for drug delivery
| Author | Akhtar N. |
| Author | Teo Y.Y. |
| Author | Najeeb M.A. |
| Author | Ahmad Z. |
| Author | Shah Z. |
| Author | Hasan M.A. |
| Available date | 2019-11-03T11:47:36Z |
| Publication Date | 2018 |
| Publication Name | International Journal of Electrochemical Science |
| Resource | Scopus |
| ISSN | 14523981 |
| Abstract | Magnetic nanoparticles (MNPs) are a class of nanoparticles, which can be manipulated using magnetic fields. Currently, MNPs are recognized as one of the most important mode as a drug carrier while they can also be potentially used as carriers for gene delivery. In this article, magnetic nanostructured lipid carriers (mNLCs) are prepared through co-precipitation method. The particle size and zeta potential, structure and thermal properties of the MNPS have been studied. The produced MNPs were also hydrophobically modified with a long chain of fatty acid namely lauric acid. These modified MNPs were mixed with nanostructured lipid carriers (NLCs) to form mNLCs. The heat capacity and flow of mNLCs was profligate in the presence of a magnetic field which is a worthy attribute for targeted drug delivery applications. � 2018 The Authors. |
| Sponsor | ACKNOWLEDGEMENTS This article was made possible by the GCC-2017-005 grant by Qatar University and NPRP9-144-3-021 grant funded by the Qatar National Research Fund (a part of Qatar Foundation). The statements made here are the total responsibility of the authors. The authors also thankfully acknowledge the University of Malaya for providing their lab facilities for completion of part of the work. |
| Language | en |
| Publisher | Electrochemical Science Group |
| Subject | Drug delivery Magnetic nanoparticles (MNPs) Magnetic nanostructured lipid carriers (mNLCs) |
| Type | Article |
| Pagination | 12040 - 12048 |
| Issue Number | 12 |
| Volume Number | 13 |
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Center for Advanced Materials Research [1379 items ]
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Mechanical & Industrial Engineering [1396 items ]