• English
    • العربية
  • العربية
  • Login
  • QU
  • QU Library
  •  Home
  • Communities & Collections
  • Help
    • Item Submission
    • Publisher policies
    • User guides
    • FAQs
  • About QSpace
    • Vision & Mission
View Item 
  •   Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • Faculty Contributions
  • College of Pharmacy
  • Pharmacy Research
  • View Item
  • Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • Faculty Contributions
  • College of Pharmacy
  • Pharmacy Research
  • View Item
  •      
  •  
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Extent of extemporaneous compounding and pattern of prescribing and use of extemporaneous medicines in a developing setting

    Thumbnail
    Date
    2019
    Author
    Yusuff, Kazeem B.
    Metadata
    Show full item record
    Abstract
    Objectives: To determine the extent of extemporaneous compounding, the prescribing pattern and use of extemporaneous medicines in a developing setting like Nigeria. Methods: A cross-sectional assessment was conducted at the Pharmacy Department of the premier teaching hospital in Nigeria. A pretested data collection form and direct inspection of packaging and labelling information were used for data extraction. Key findings: About 100% (678) of the extemporaneous products were liquid dosage form made with trituration using crushed tablets (76.5%, 519), opened capsules (17.6%, 119) and broken ampoules (5.9%, 40), and the majority (77.2%, 524) were dispensed to inpatients. The ten most frequent extemporaneous preparations were zinc gluconate (11.1%, 75), spironolactone (10%, 60), hydrochlorothiazide (9%, 60), captopril (9%, 60), hydroxyurea (8.1%, 55), furosemide (6%, 40), lisinopril (5.2%, 35), phenytoin (5.2%, 35), carbamazepine (4.1%, 28) and enalapril (4%, 27). Simple syrup and amaranth solution were the most frequently used excipients (97.2%, 659). Packaging was done with white plastic bottles (100%, 678). No labelling information was provided on storage condition and expiry date, and the compounding pharmacists' lacked access to key information on the stability, bioavailability, efficacy and safety of extemporaneously prepared medicines. Conclusions: The extent of compounding and use of extemporaneous products is considerable and remain an importance source of critical access to essential medicines for children with cardiovascular and neurological disorders, and electrolyte imbalance and nutritional deficiencies in both the inpatient and ambulatory settings. However, the limited access to information on the stability, efficacy and safety of extemporaneous products may potentially expose patients to harm. - 2019 Royal Pharmaceutical Society
    DOI/handle
    http://dx.doi.org/10.1111/jphs.12297
    http://hdl.handle.net/10576/14997
    Collections
    • Pharmacy Research [‎1426‎ items ]

    entitlement


    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Home

    Submit your QU affiliated work

    Browse

    All of Digital Hub
      Communities & Collections Publication Date Author Title Subject Type Language Publisher
    This Collection
      Publication Date Author Title Subject Type Language Publisher

    My Account

    Login

    Statistics

    View Usage Statistics

    About QSpace

    Vision & Mission

    Help

    Item Submission Publisher policiesUser guides FAQs

    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Video