Show simple item record

AuthorAlhadrami, Hani A.
AuthorSyed, Raza ur Rehman
AuthorZahid, Alap Ali
AuthorAhmed, Rashid
AuthorHasan, Shajia
AuthorHasan, Anwarul
Available date2020-07-23T19:50:10Z
Publication Date2019
Publication NameJournal of Healthcare Engineering
ResourceScopus
URIhttp://dx.doi.org/10.1155/2019/3290370
URIhttp://hdl.handle.net/10576/15337
AbstractHeart valve (HV) diseases are among the leading causes of cardiac failure and deaths. Of the various HV diseases, damaged HV leaflets are among the primary culprits. In many cases, impaired HV restoration is not always possible, and the replacement of valves becomes necessary. Bioprosthetic HVs have been used for the replacement of the diseased valves, which is obtained from the sources of bovine and porcine origin, while tissue-engineered heart valves (TEHV) have emerged as a promising future solution. The bioprosthetic valves are prone to become calcified, and thus they last for only ten to fifteen years. The adequate understanding of the correlations between the biomechanics and rheological properties of native HV tissues can enable us to improve the durability of the bioprosthetic HV as well as help in the development of tissue-engineered heart valves (TEHV). In this study, the structural and rheological properties of native bovine aortic HV and pericardium tissues were investigated. The microstructures of the tissues were investigated using scanning electron microscopy, while the rheological properties were studied using oscillatory shear measurement and creep test. The reported results provide significant insights into the correlations between the microstructure and viscoelastic properties of the bovine aortic HV and pericardium tissues.
Languageen
PublisherHindawi Limited
SubjectBioprosthetic
Tissue-Engineered Heart Valves
TitleStructure and Rheological Properties of Bovine Aortic Heart Valve and Pericardium Tissue: Implications in Bioprosthetic and Tissue-Engineered Heart Valves
TypeArticle
Volume Number2019
dc.accessType Open Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record