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SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections
(
Elsevier
, 2021 , Article)
By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...
A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing
(
Springer Verlag
, 2021 , Article Review)
Coronavirus disease (COVID-19) pandemic is instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of March 13, 2021, more than 118.9 million cases were infected with COVID-19 worldwide. SARS-CoV-2 ...
Evaluation of antibody response in symptomatic and asymptomatic covid-19 patients and diagnostic assessment of new IgM/IgG elisa kits
(
MDPI
, 2021 , Article)
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This study aims to study the immune response and evaluate the performances of four new IgM and five IgG enzyme-linked immunosorbent assay (ELISA) kits for detecting ...
Designing evaluation framework for the empirical assessment of COVID-19 mobile apps in Pakistan
(
Elsevier
, 2022 , Article)
The significant proliferation in the mobile health applications (Apps) amidst Coronaviruses disease 2019 (COVID-19) resulted in decision making problems for healthcare professionals, decision makers and mobile users in ...
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
(
Frontiers Media
, 2021 , Article)
Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...
Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild-to-moderate SARS-CoV-2 in Qatar
(
Elsevier
, 2022 , Article)
ObjectivesTo estimate the real-world effectiveness of sotrovimab against severe, critical, or fatal COVID-19 in Qatar at a time in which most SARS-CoV-2 incidences occurred due to the BA.2 Omicron subvariant. MethodsWe ...
Evaluation of anakinra in the management of patients with COVID-19 infection: A randomized clinical trial
(
Frontiers Media S.A.
, 2023 , Article)
Background: The global COVID-19 pandemic led to substantial clinical and economic outcomes with catastrophic consequences. While the majority of cases has mild to moderate disease, minority of patients progress into severe ...
Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
(
IMR Press
, 2022 , Article Review)
Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ...
Association between Multimorbidity and COVID-19 Mortality in Qatar: A Cross-Sectional Study
(
PagePress
, 2023 , Article)
This study assessed the association between multimorbidity and mortality from COVID-19 in the Middle East and North Africa region, where such data are scarce. We conducted a cross-sectional study using data of all cases ...
ANTIBODY DEPENDENT ENHANCEMENT (ADE) - CAUSE OF DISEASE SEVERITY IN CORONAVIRUS INFECTED AND/OR VACCINATED INDIVIDUALS
(2024 , Master Thesis)
Aim: This study evaluated the potential for ADE in serum samples from patients exposed to SARS-CoV-2 (Severe acute respiratory syndrome-coronavirus-2) and MERS-CoV (Middle East Respiratory Syndrome-coronavirus). For ...