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    Factors associated with medication adherence among patients with diabetes in the Middle East and North Africa region: A systematic mixed studies review

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    Factors associated with medication adherence Diabetes Research and Clinica; Practice.pdf (1.432Mb)
    Date
    2017-07-31
    Author
    Myriam, Jaam
    Ibrahim, Mohamed Izham Mohamed
    Kheir, Nadir
    Awaisu, Ahmed
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    Abstract
    Multiple systematic reviews were conducted investigating factors associated with medication adherence worldwide. However, investigations from the Middle East and North Africa (MENA) region were largely underrepresented in those reviews. Therefore, the objective of this systematic review is to identify the factors influencing medication adherence among patients with diabetes in the MENA region. A systematic literature search was conducted through Cochrane Library, EBSCO, EMBASE, Google Scholar, ISI Web of Science, PubMed, ScienceDirect, SCOPUS, and ProQuest. Studies were included if they determined factors associated with medication adherence among patients with diabetes within the MENA region. Quality was assessed using Crow Critical Appraisal Tool. Thirty primary studies from 10 MENA countries were included. The factors associated with medication adherence were categorized into demographics-related; disease- and medication-related; perception, attitude and psychological feelings-related; and societal-related factors. Positively associated factors included knowledge about the disease and medications, regular follow-up visits, and patients’ positive beliefs about effectiveness and motivations about medications, while negatively associated factors included forgetfulness, side effects, and polypharmacy. Factors associated with medication adherence among patients with diabetes in the MENA region are highly diverse. The identified factors can serve as potential targets for culturally-relevant interventions to improve medication adherence and overall health outcomes.
    URI
    https://www.sciencedirect.com/science/article/pii/S0168822716318587
    DOI/handle
    http://dx.doi.org/10.1016/j.diabres.2017.04.015
    http://hdl.handle.net/10576/17311
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