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Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival.
(
Frontiers Media
, 2020 , Article)
Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular abnormalities. Among these EVs, microparticles (MPs) are vesicles directly ...
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
(
Dove Medical Press
, 2020 , Article)
Venetoclax (VCX) is a selective BCL-2 inhibitor approved for the treatment of leukemia and lymphoma. However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic ...
EMT Factors and Metabolic Pathways in Cancer.
(
Frontiers Media
, 2020 , Article)
The epithelial-mesenchymal transition (EMT) represents a biological program during which epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is normally observed during organismal development, ...
Using YouTube to Learn Anatomy: Perspectives of Jordanian Medical Students
(
hindawi
, 2020 , Article)
The study is aimed at exploring the popularity, impact, and usefulness of using YouTube in learning anatomy as perceived by Jordanian medical students studying at Jordan University of Science and Technology. Methods. The ...
The Composition and Writing of the Qurʾān: Old Explanations and New Evidence
(
Qatar University Press
, 2020 , Article)
يعارض هذا البحث الفكرة السائدة لدى الكثير من الباحثين الغربيين منذ مطلع القرن السابق بأن القرآن الكريم لم يكتمل ككتاب منزّل خلال حياة النبي بل أخذ شكله النهائي بعد وفاته بفترة غير قصيرة. ومقابل هذه الفكرة يسلط الضوء على ...
White Button Mushroom, Agaricus bisporus (Agaricomycetes), and a Probiotics Mixture Supplementation Correct Dyslipidemia without Influencing the Colon Microbiome Profile in Hypercholesterolemic Rats
(
Begell House
, 2020 , Article)
Consumption of foods rich in dietary fiber has attracted considerable attention for lowering blood cholesterol and triglycerides through attenuation of gut microbiome. Diets rich in fiber may provide substrates for microbes ...
Rehabilitation needs in individuals with knee OA in rural Western Cape, South Africa: an exploratory qualitative study
(
Cambridge University Press
, 2020 , Article)
Background: Current clinical practice guidelines have suggested that each individual with knee
osteoarthritis (OA) should receive three core treatments from their health care provider. These
core treatments comprise of ...
Obesity is associated with depression in Malaysian schoolchildren: A cross-sectional study
(
Universitas Indonesia
, 2020 , Article)
Background: Overweight and obesity, which may lead to depression, have become prevalent among children worldwide. Hence, this study aimed to measure obesity and depression among schoolchildren in Kuantan. Methods: This ...
Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine.
(
Springer
, 2020 , Article)
Cadmium (Cd) is a naturally occurring toxic heavy metal with no known essential biological functions. Exposure to Cd increases the risk of cardiovascular disease by disrupting vascular homeostasis at the endothelium. The ...
Healthcare practitioners’ views of their role in addressing the medical comorbidites of people with mental illness
(
Fortune Journals
, 2020 , Article)
Objectives: To explore the views and experiences of different healthcare professionals in Qatar about their role addressing the medical comorbidities of people with serious mental illness (SMI).
Subjects and Methods: ...