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Targeting HER2 expression in cancer: New drugs and new indications.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2020 , Article)
Functional activation of human epidermal growth factor receptor 2 (HER2) has been shown to strongly promote carcinogenesis, leading to the investigation of HER2-directed agents in cancers with HER2 genomic alterations. ...
A Successful Treatment of Encapsulating Peritoneal Sclerosis in an Adolescent Boy on Long-term Peritoneal Dialysis: A Case Report.
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First Faculty of Medicine Charles University
, 2020 , Article)
Encapsulating peritoneal sclerosis (EPS) is a rare life-threatening complication associated with peritoneal dialysis (PD). EPS is characterized by progressive fibrosis and sclerosis of the peritoneum, with the formation ...
Unexpected adrenal pheochromocytoma associated with a generalized tonic-clonic seizure in a prepubertal boy: A case report.
(
Lippincott, Williams & Wilkins
, 2021 , Article)
Pheochromocytoma (PHEO) is a rare neuroendocrine tumor arising from chromaffin cells of the adrenal medulla. Most pediatric PHEOs are functional tumors, and clinical manifestations are related to catecholamine hypersecretion ...
Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas.
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BJBMS
, 2020 , Article)
Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental ...
CO-PREVALENCE OF HUMAN PAPILLOMAVIRUS AND EPSTEIN BARR VIRUS IN HEALTHY BLOOD DONORS IN QATAR
(
Qatar University Press
, 2020 , Poster)
Introduction: Infections with human oncoviruses such as high-risk human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are globally prevalent in the adult population. Both viruses are strongly associated with several ...
Co-Incidence of Human Papillomaviruses and Epstein-Barr Virus is Associated with Advanced Tumor Stage: A Tissue Microarray Study of Head and Neck Cancers
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Qatar University Press
, 2020 , Poster)
Background: Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), are known oncoviruses and can be co-present and hence cooperate in the development of human carcinomas, including head and neck. Methods: We herein ...
Comparison of co-presence of Epstein-Barr virus and high-risk human papillomaviruses in colorectal cancers in the Middle East Region
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Qatar University Press
, 2020 , Poster)
Background: Several studies have shown the presence of onco viral DNA in colorectal tumor tissues. Viral infection by onco-viruses such as Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are well-known to be ...
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
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Springer
, 2020 , Article)
Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ...
Bowel Dilatation on Initial Plane Abdominal Radiography May Help to Assess the Severity of Necrotizing Enterocolitis in Preterm Infants.
(
MDPI
, 2020 , Article)
Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency associated with prematurity. Timely diagnosis and adequate treatment are crucial to reduce the morbidity and mortality of the ...
Oncoproteins of High-Risk HPV and EBV Cooperate to Enhance Cell Motility and Invasion of Human Breast Cancer Cells Erk1/Erk2 and β-Catenin Signaling Pathways.
(
Frontiers Media
, 2021 , Article)
Breast cancer is a leading cause of death in women around the world. Most breast cancer-related deaths are a result of complications from the metastatic spread. Several recent studies reported that high-risk human ...