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Traumatic brain injury: Oxidative stress and novel anti-oxidants such as mitoquinone and edaravone
(
MDPI
, 2020 , Article Review)
Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually ...
Glycomic and Glycoproteomic Techniques in Neurodegenerative Disorders and Neurotrauma: Towards Personalized Markers
(
MDPI
, 2022 , Article Review)
The proteome represents all the proteins expressed by a genome, a cell, a tissue, or an organism at any given time under defined physiological or pathological circumstances. Proteomic analysis has provided unparalleled ...
Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome
(
MDPI
, 2021 , Article Review)
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder affecting a vast population worldwide; it is linked with anovulation, mitochondrial dysfunctions and hormonal disbalance. Mutations in mtDNA ...
Cardiac autonomic neuropathy: A progressive consequence of chronic low-grade inflammation in type 2 diabetes and related metabolic disorders
(
MDPI
, 2020 , Article Review)
Cardiac autonomic neuropathy (CAN) is one of the earliest complications of type 2 diabetes (T2D), presenting a silent cause of cardiovascular morbidity and mortality. Recent research relates the pathogenesis of cardiovascular ...
Epac in vascular smooth muscle cells
(
MDPI
, 2020 , Article Review)
Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process ...
Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications
(
Frontiers Media S.A.
, 2022 , Article Review)
There have been significant advances, particularly over the last 20 years, in the identification of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease states, particularly cancer and other ...
Ace2 is an adjacent element of atherosclerosis and covid-19 pathogenesis
(
MDPI
, 2021 , Article Review)
COVID-19 is a highly contagious new infection caused by the single-stranded RNA SarsCoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese province of Wuhan. The virus presumably crossed ...
Small Cell Lung Carcinoma: Current Diagnosis, Biomarkers, and Treatment Options with Future Perspectives
(
MDPI
, 2023 , Article Review)
Small cell lung cancer (SCLC) is an aggressive malignancy characterized by rapid proliferation, early dissemination, acquired therapy resistance, and poor prognosis. Early diagnosis of SCLC is crucial since most patients ...
The prospect of synthesis of PES/PEG blend membranes using blend NMP/DMF for CO2/N2 separation
(
Springer Science and Business Media B.V.
, 2021 , Article Review)
Carbon dioxide (CO2) emissions have been the root cause for anthropogenic climate change. Decarbonisation strategies, particularly carbon capture and storage (CCS) are crucial for mitigating the risk of global warming. ...
The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
(
Springer Science and Business Media B.V.
, 2023 , Article Review)
Background and Aim
The impact of multiple risk factors on COVID-19 mortality has been previously reported in multiple systematic reviews and meta-analyses. The aim of this review is to provide a comprehensive update on ...