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Now showing items 851-860 of 960
Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
(
Taylor and Francis Ltd.
, 2023 , Article Review)
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer ...
Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
(
Wiley
, 2022 , Article Review)
Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ...
Epidemiology of herpes simplex virus type 1 in Canada: systematic review, meta-analyses, and meta-regressions
(
Frontiers Media SA
, 2023 , Article Review)
Background: The objective of this study was to characterize herpes simplex virus type 1 (HSV-1) epidemiology in Canada.
Methods: HSV-1 publications as recent as December 6, 2021 were systematically reviewed, synthesized, ...
Oncolytic viruses as nanomedicines against the tumor microenvironment
(
AMG Transcend Association
, 2021 , Article Review)
The tumor microenvironment is best described as the battleground for fighting cancer and the host immune system. Contrary to primitive beliefs that cancer growth and progression are solely dependent on cancer cells, recent ...
Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
(
Frontiers Media
, 2023 , Article Review)
Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ...
Metabolic-associated fatty liver disease: a selective review of pathogenesis, diagnostic approaches, and therapeutic strategies.
(
Frontiers Media
, 2024 , Article Review)
Metabolic associated fatty liver disease (MAFLD) is a novel terminology introduced in 2020 to provide a more accurate description of fatty liver disease associated with metabolic dysfunction. It replaces the outdated term ...
Biomaterials in Traumatic Brain Injury: Challenges and Perspectives
(
Preprints
, 2023 , Article Review)
Traumatic brain injury (TBI) is among the leading causes of mortality and long-term impairment globally. TBI has a dynamic pathology encompassing a variety of metabolic and molecular events that occur in two phases, primary ...
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
(
MDPI
, 2024 , Article Review)
Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...
Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer
(
Institute for Ionics
, 2023 , Article Review)
Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene expression and protein functions and are implicated in various biological processes including cancer. Notably, breast cancer has a ...
Visible light communication for intelligent transportation systems: A review of the latest technologies
(
Elsevier
, 2021 , Article Review)
In seeking to improve traffic congestion and safety on roads and highways, there has been an increased interest in intelligent transportation systems (ITS). The emerging visible light communication (VLC) technology is a ...