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Serum vitamin D concentrations are non-linearly related to breast cancer risk in postmenopausal women
(
Qatar University Press
, 2021 , Poster)
Background: Post-menopausal women are at high risk for breast cancer. The association between serum 25-hydroxyvitamin D [25(OH)D] concentration and breast cancer in post-menopausal women is not well understood. Objectives: ...
Systemic properties of carcinogenesis: lessons from studies on the Earth and in the Space
(
Qatar University Press
, 2020 , Poster)
Background: Hundreds of proteins and genes are involved in initiation and growth of tumors. These proteins and genes act in coordinated ways, and their relations are visualized as networks. Networks are more accurate ...
Post-translational modifications of albumin in cancer a rich source for diagnostic and monitoring of treatment
(
Qatar University Press
, 2020 , Poster)
Albumin is in contact with all cells in a body. This major protein in a plasma accesses all tissues and organs and has a number of different roles. Albumin was found to have more than 50 post-translational modifications ...
Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
(
Taylor and Francis Ltd
, 2018 , Article Review)
Introduction: Exploration in the field of epigenetics has revealed the diverse roles of the protein arginine methyltransferase (PRMT) family of proteins in multiple disease states. These findings have led to the development ...
Is curcumin at the threshold of therapeutic effectiveness on patients with colon cancer? – A systematic review
(
Qatar University Press
, 2021 , Poster)
Curcumin, obtained from Curcuma longa, has been the subject of decades of scientific investigation on its therapeutic usefulness. It is reported to possess several therapeutic properties, of which anti-colon cancer is of ...
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
(
Qatar University Press
, 2021 , Poster)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ...
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
(
BioMed Central Ltd
, 2023 , Article)
Background: In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected ...
Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments
(
BMC
, 2022 , Article Review)
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical ...
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids
(
Elsevier
, 2021 , Article)
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of human diseases including cancer. In this line, now it has become evident that ROS level/concentration is a major factor in the growth, ...
miRNAs as novel immunoregulators in cancer
(
Elsevier
, 2021 , Article Review)
The immune system is a well-known vital regulator of tumor growth, and one of the main hallmarks of cancer is evading the immune system. Immune system deregulation can lead to immune surveillance evasion, sustained cancer ...