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Claudin-1, A Double-Edged Sword in Cancer.
(
MDPI
, 2020 , Article Review)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
Association of genes with phenotype in autism spectrum disorder.
(
Impact Journals
, 2019 , Article Review)
Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ...
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
(
BMC
, 2020 , Article Review)
Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ...
Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.
(
MDPI
, 2020 , Article Review)
Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly recognized as both a disorder of mental health and social burden, but also as an anxiety disorder characterized by fear, stress, and ...
Anticancer potential of sanguinarine for various human malignancies
(
Future Medicine Ltd.
, 2017 , Article Review)
Sanguinarine (Sang) - a benzophenanthridine alkaloid extracted from Sanguinaria canadensis - exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory activities on tumor cells of various cancer types as ...
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
(
BMC
, 2021 , Article Review)
Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...
Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
(
Frontiers Media
, 2021 , Article Review)
Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased ...
RAS-mediated oncogenic signaling pathways in human malignancies
(
Elsevier
, 2018 , Article Review)
Abnormally activated RAS proteins are the main oncogenic driver that governs the functioning of major signaling
pathways involved in the initiation and development of human malignancies. Mutations in RAS genes and
or its ...
Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways
(
Elsevier
, 2022 , Article Review)
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and histopathological features. The biology of CTCL is complex ...
Nano-vitamin C: A promising candidate for therapeutic applications
(
Elsevier
, 2023 , Article Review)
Vitamin C is an important nutrient implicated in different physiological functions in humans. Despite its important biological functions, therapeutic applications of vitamin C are rare and its use is further impacted by ...