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Carboxybetaine Modified Interface for Electrochemical Glycoprofiling of Antibodies Isolated from Human Serum
(
American Chemical Society
, 2015 , Article)
Impedimetric lectin biosensors capable of recognizing two different carbohydrates (galactose and sialic acid) in glycans attached to antibodies isolated from human serum were prepared. The first step entailed the modification ...
Glycoprofiling as a novel tool in serological assays of systemic sclerosis: A comparative study with three bioanalytical methods
(
Elsevier
, 2015 , Article)
Systemic sclerosis (SSc) is an autoimmune disease seriously affecting patient’s quality of life. The heterogeneity of the disease also means that identification and subsequent validation of biomarkers of the disease is ...
Nanomaterial-based biosensors for detection of prostate specific antigen
(
Springer-Verlag Wien
, 2017 , Article Review)
Screening serum for the presence of prostate specific antigen (PSA) belongs to the most common approach for the detection of prostate cancer. This review (with 156 refs.) addresses recent developments in PSA detection based ...
Highly stable Ti3C2Tx (MXene)/Pt nanoparticles-modified glassy carbon electrode for H2O2 and small molecules sensing applications
(
Elsevier B.V.
, 2018 , Article)
© 2018 Elsevier B.V. Electrochemical performance of a 2D Ti3C2Tx (MXene, where T: [dbnd]O, –OH, –F) sheets modified with Pt nanoparticles (PtNPs) was investigated. The results showed that Ti3C2Tx/PtNP nanocomposite deposited ...
Glycomics of prostate cancer: updates
(
Taylor and Francis Ltd
, 2019 , Article)
Introduction: Prostate cancer (PCa) is a life-threatening disease affecting millions of men. The current best PCa biomarker (level of prostate-specific antigen in serum) lacks specificity for PCa diagnostics and this is ...
Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes
(
John Wiley and Sons Inc.
, 2017 , Article Review)
This review comprehensively covers the most recent achievements (from 2013) in the successful integration of nanomaterials in the field of glycomics. The first part of the paper addresses the beneficial properties of ...
PH-Switchable Interaction of a Carboxybetaine Ester-Based SAM with DNA and Gold Nanoparticles
(
American Chemical Society
, 2017 , Article)
We describe a self-assembled monolayer (SAM) on a gold surface with a carboxybetaine ester functionality to control the interaction between DNA and gold nanoparticles via pH. The negatively charged phosphate backbone of ...
Novel analysis of glycan structures: Nanoscale approach
(
Avestia Publishing
, 2016 , Conference Paper)
Glycans are complex saccharide moieties covering all cell surfaces - presented on different biomolecules. Almost 75% of all proteins are glycosylated, and these glycans can form thousands of different structures.[1] Moreover, ...
Mixed Zwitterion-Based Self-Assembled Monolayer Interface for Impedimetric Glycomic Analyses of Human IgG Samples in an Array Format
(
American Chemical Society
, 2016 , Article)
An impedimetric lectin biosensor for the detection of changes in the glycan structure of antibodies isolated from human serum is here correlated with the progression of rheumatoid arthritis (RA). The biosensor was built ...
Simple, Reversible, and Fast Modulation in Superwettability, Gradient, and Adsorption by Counterion Exchange on Self-Assembled Monolayer
(
American Chemical Society
, 2016 , Article)
A simple fabrication method for preparation of surfaces able to switch from superhydrophobic to superhydrophilic state in a reversible and fast way is described. A self-assembled monolayer (SAM) consisting of quaternary ...