Search
Now showing items 41-50 of 99
Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group
(
Academy of Sciences and Arts of Bosnia and Herzegovina
, 2022 , Article)
In the present review, we briefly discuss the breakthrough advances in precision medicine using a tumor-agnostic approach and focus on BRAF treatment modalities, the mechanisms of resistance and the diagnostic approach in ...
Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas.
(
BJBMS
, 2020 , Article)
Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental ...
Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy
(
Karger
, 2019 , Article)
We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma (GN) during the diagnostic work up of alopecia areata (AA). Clinical Presentation and Intervention Laboratory investigations revealed ...
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
(
MDPI
, 2020 , Article)
Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ...
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
(
Frontiers Media
, 2020 , Article)
Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ...
Bilateral Morgagni hernia in a two-month-old infant with a history of umbilical cord hernia status-post repair in neonatal period
(
Elsevier
, 2022 , Other)
Morgagni hernias (MH) are a rare form of congenital diaphragmatic hernia (CDH) characterized by herniation of abdominal contents into the thoracic cavity through a retrosternal diaphragmatic defect. MH constitutes <5% of ...
Alpha-methylacyl-CoA Racemase (AMACR) Protein is Upregulated in Early Proliferative Lesions of the Breast Irrespective of Apocrine Differentiation
(
Elsevier
, 2022 , Other)
Alpha-methylacyl-CoA racemase (AMACR/P504S) is a mitochondrial and peroxisomal enzyme involved in the branched-chain fatty acid and bile acid metabolism. AMACR is a useful diagnostic biomarker for prostate carcinomas and ...
An infant with ankyloblepharon filiforme adnatum associated with a cleft lip and palate: A case report
(
Elsevier
, 2022 , Other)
Ankyloblepharon filiform adnatum (AFA) is a rare but potentially ambylogenic congenital anomaly characterized by a partial or complete fusion of the eyelid margins.1 Although AFA has been reported as an isolated finding, ...
TERT gene fusions characterize a subset of metastatic Leydig cell tumors
(
Elsevier
, 2021 , Article)
Objective: Metastatic Leydig cell tumors (LCT) are rare, difficult to treat malignancies without known underlying molecular-genetic events. An index case of metastatic LCT showed an LDLR-TERT gene fusion upon routine genetic ...
2020 consensus guideline for optimal approach to the diagnosis and treatment of HER2-positive breast cancer in Bosnia and Herzegovina.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2020 , Article)
The HERe2cure project, which involved a group of breast cancer experts, members of multidisciplinary tumor boards from healthcare institutions in Bosnia and Herzegovina, was initiated with the aim of defining an optimal ...