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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte.
(
Wiley
, 2018 , Article)
In the central nervous system (CNS), oligodendrocytes are the glial element in charge of myelin formation. Obtaining an overall presence of oligodendrocyte precursor cells/oligodendrocytes (OPCs/OLs) in culture from different ...
Growth factor releasing core-shell polymeric scaffolds for tissue engineering applications
(
Institute of Electrical and Electronics Engineers Inc.
, 2019 , Conference Paper)
Tissue engineering is the use of a combination of cells, biomaterials and appropriate signals to repair or improve the functions of damaged tissues. Our group is exploiting various approaches to effectively encapsulate ...
Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury.
(
Frontiers Media
, 2017 , Article)
Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The ...
Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells.
(
Wiley
, 2018 , Article)
Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types such as cartilage, bone, and fat cells. Recent studies have shown that induction of MSCs in vitro by growth factors including ...
Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential.
(
Nature Publishing Group
, 2017 , Article)
The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ...
Titanium Nanorods Loaded PCL Meshes with Enhanced Blood Vessel Formation and Cell Migration for Wound Dressing Applications.
(
Wiley
, 2019 , Article)
Proper management of nonhealing wounds is an imperative clinical challenge. For the effective healing of chronic wounds, suitable wound coverage materials with the capability to accelerate cell migration, cell proliferation, ...
CTGF Loaded Electrospun Dual Porous Core-Shell Membrane For Diabetic Wound Healing
(
Dove Medical Press Ltd.
, 2019 , Article)
Purpose: Impairment of wound healing is a major issue in type-2 diabetes that often causes chronic infections, eventually leading to limb and/or organ amputation. Connective tissue growth factor (CTGF) is a signaling ...
Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
(
Wiley
, 2020 , Article)
© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ...
Engineered Biomaterials to Enhance Stem Cell-Based Cardiac Tissue Engineering and Therapy
(
Wiley
, 2016 , Article)
Cardiovascular disease is a leading cause of death worldwide. Since adult cardiac cells are limited in their proliferation, cardiac tissue with dead or damaged cardiac cells downstream of the occluded vessel does not ...
Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications.
(
Springer Verlag
, 2018 , Article)
Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the ...