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Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update.
(
Frontiers Media
, 2020 , Article Review)
Sperm-specific phospholipase C zeta (PLCζ) is widely considered to be the physiological stimulus responsible for generating calcium (Ca) oscillations that induce egg activation and early embryonic development during mammalian ...
Glycogen-rich Clear Cell Carcinoma of the Breast: A Comprehensive Review.
(
Lippincott, Williams & Wilkins
, 2020 , Article Review)
Glycogen-rich clear cell carcinoma (GRCC) is a very rare form of primary breast cancer (<0.1% of all breast cancers). It is characterized by the presence of neoplastic cells with a glycogen-abundant clear cytoplasm (the ...
Mapping hospital antimicrobial stewardship programmes in the Gulf Cooperation Council states against international standards: a systematic review
(
Elsevier
, 2020 , Article Review)
BackgroundWhile there is evidence of implementation of antimicrobial stewardship programmes (ASPs) in the Gulf Cooperation Council (GCC) states, there has been limited benchmarking and mapping to international standards ...
Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit?
(
Frontiers Media
, 2020 , Article Review)
Respiratory viruses, including coronaviruses, are known to have a high incidence of infection during winter, especially in temperate regions. Dry and cold conditions during winter are the major drivers for increased ...
The Microbiota and Gut-Related Disorders: Insights from Animal Models
(
MDPI
, 2020 , Article Review)
Over the past decade, the scientific committee has called for broadening our horizons in understanding host–microbe interactions and infectious disease progression. Owing to the fact that the human gut harbors trillions ...
The Spectrum of Mutations of Homocystinuria in the MENA Region
(
MDPI
, 2020 , Article Review)
Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ...
Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis.
(
Springer
, 2020 , Article Review)
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an abnormal fibrotic response involving vast ...
Potential Adverse Effects of Resveratrol: A Literature Review.
(
MDPI
, 2020 , Article Review)
Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive ...
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
(
BMC
, 2020 , Article Review)
Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ...
Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities
(
Elsevier B.V.
, 2021 , Article Review)
The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. ...