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AuthorPeter V., Coyle
AuthorChemaitelly, Hiam
AuthorBen Hadj Kacem, Mohamed Ali
AuthorAbdulla Al Molawi, Naema Hassan
AuthorEl Kahlout, Reham Awni
AuthorGilliani, Imtiaz
AuthorYounes, Nourah
AuthorAl Anssari, Ghada Ali A.A.
AuthorAl Kanaani, Zaina
AuthorAl Khal, Abdullatif
AuthorAl Kuwari, Einas
AuthorButt, Adeel A.
AuthorJeremijenko, Andrew
AuthorKaleeckal, Anvar Hassan
AuthorLatif, Ali Nizar
AuthorShaik, Riyazuddin Mohammad
AuthorAbdul Rahim, Hanan F.
AuthorNasrallah, Gheyath K.
AuthorYassine, Hadi M.
AuthorAl Kuwari, Mohamed Ghaith
AuthorAl Romaihi, Hamad Eid
AuthorAl-Thani, Mohamed H.
AuthorBertollini, Roberto
AuthorAbu-Raddad, Laith J.
Available date2021-10-20T09:18:27Z
Publication Date2021-06-25
Publication NameiScience
Identifierhttp://dx.doi.org/10.1016/j.isci.2021.102646
CitationCoyle, P. V., Chemaitelly, H., Kacem, M. A. B. H., Al Molawi, N. H. A., El Kahlout, R. A., Gilliani, I., ... & Abu-Raddad, L. J. (2021). SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals. Iscience, 102646.
ISSN25890042
URIhttps://www.sciencedirect.com/science/article/pii/S2589004221006143
URIhttp://hdl.handle.net/10576/24585
AbstractThe study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens for 112,941 individuals (∼10% of Qatar's urban population) attending for routine/other clinical care between May 12 and September 9, 2020. Seropositivity was 13.3% (95% confidence interval [CI] = 13.1–13.6%) and was independently associated with sex, age, nationality, clinical care encounter type, and testing date. Median optical density (antibody titer) among antibody-positive persons was 27.0 (range = 1.0–150.0), with higher values associated with age, nationality, clinical care encounter type, and testing date. Seropositivity by nationality was positively correlated with the likelihood of having higher antibody titers (Pearson correlation coefficient = 0.85; 95% CI = 0.47–0.96). Less than two in every 10 individuals in Qatar's urban population had detectable antibodies against SARS-CoV-2, suggesting this population is still far from herd immunity and at risk of subsequent infection waves. Higher antibody titer appears to be a biomarker of repeated exposures to the infection.
Languageen
PublisherElsevier
SubjectHealth informatics
Public health
Infection control in health technology
Immunology
TitleSARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals
TypeArticle
Issue Number6
Volume Number24
Open Access user License http://creativecommons.org/licenses/by/4.0/


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