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المؤلفBadulla, W. F. S.
المؤلفAlshakka, M.
المؤلفIbrahim, Mohamed Izham Mohamed
تاريخ الإتاحة2022-04-10T10:25:32Z
تاريخ النشر2020
اسم المنشورBioMed Research International
المصدرScopus
المعرّفhttp://dx.doi.org/10.1155/2020/1810290
معرّف المصادر الموحدhttp://hdl.handle.net/10576/29403
الملخصBackground. There is a rapid deterioration in the effectiveness of antibiotics due to the global prevalence of bacterial antimicrobial resistance (AMR). AMR can cause an increase in mortality and morbidity due to treatment failures and a lack of effective therapy. Objective. The purpose of this study was to evaluate the AMR pattern of different bacterial isolates at hospitals and laboratories. Materials and Methods. A cross-sectional study from March 2019 to June 2019 was conducted at different governmental and private hospitals and laboratories in Aden, Yemen. Age, sex, specimen type, bacterial isolates, and antibiotic susceptibility pattern were collected using a data extraction sheet. Descriptive statistics were used for data analysis. Result. Data were recorded for 412 patients from whom 20 clinical specimens were collected and analyzed. The most common bacteria isolated were Staphylococcus spp. (n=172, 41.74%), E. coli (n=164, 39.80%), Pseudomonas spp. (n=37, 8.98%), and Klebsiella pneumoniae (n=18, 4.36%); other bacteria were less common. The overall bacterial resistance was highest against the combination of sulfamethoxazole with trimethoprim (73.12%), followed by amoxicillin and clavulanate (65.19%). The cephalosporin antibiotics also showed high resistance rates. The study also showed moderate bacterial resistance to gentamycin (32.65%), azithromycin (29.92%), cefoxitin (62.65%), and ciprofloxacin (25.60%). Ertapenem (16.67%) and levofloxacin (15.56%) had the lowest resistance rates. Conclusion. There was a high percentage of bacteria resistant to several antibiotics. Antibiotic susceptibility testing is a prerequisite guide for the selection of appropriate antibiotic therapy for bacterial infections.
راعي المشروعhttps://orcid.org/0000-0003-1145-860X Badulla Wafa F. S. aden.wf.77@gmail.com 1 Alshakka Mohammed alshakka400@gmail.com 2 https://orcid.org/0000-0001-9757-3574 Mohamed Ibrahim Mohamed Izham mohamedizham@qu.edu.qa 3 Domingo Pere 1 Department of Analytical Chemistry Faculty of Pharmacy Aden University Aden Yemen aden-univ.net 2 Section of Clinical Pharmacy Faculty of Pharmacy Aden University Aden Yemen aden-univ.net 3 Department of Clinical Pharmacy and Practice College of Pharmacy QU Health Qatar University Doha Qatar qu.edu.qa 2020 23 4 2020 2020 11 02 2020 02 04 2020 23 4 2020 2020 Copyright � 2020 Wafa F. S. Badulla et al. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The publication of this article was funded by Qatar National Library.
اللغةen
الناشرHindawi Limited
الموضوعamoxicillin plus clavulanic acid
antibiotic agent
azithromycin
cefepime
cefotaxime
cefoxitin
ceftazidime
ceftriaxone
cefuroxime
cephalosporin
ciprofloxacin
cotrimoxazole
ertapenem
gentamicin
levofloxacin
antiinfective agent
adult
antibiotic resistance
antibiotic sensitivity
Article
bacterium isolate
Candida albicans
child
controlled study
العنوانAntimicrobial Resistance Profiles for Different Isolates in Aden, Yemen: A Cross-Sectional Study in a Resource-Poor Setting
النوعArticle
رقم المجلد2020
dc.accessType Abstract Only


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