بحث بسيط
السجلات المعروضة 21 -- 30 من 55
The Cytotoxicity Of “Al-Siddir” Tree “Ziziphus Spina Christi” Methanolic Leaves Extract on Her-2 Positive Breast Cancer
(Pharmacy, 2024 , Master Thesis)
HER-2 positive is a subtype of breast cancer that acquires poor prognosis and low survival rates. Targeted therapy is one of the main approaches that are used for the treatment of HER-2-positive breast cancer. However, it ...
INVESTIGATING THE ROLE OF THE ARYL HYDROCARBON RECEPTOR AND BCL-2 FAMILY PROTEINS IN OVARIAN CANCER STEM CELLS DEVELOPMENT AND CHEMORESISTANCE
(Pharmacy, 2024 , Dissertation)
Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC),
the most lethal gynecological malignancy, is clinically presented with chemoresistance
and a higher relapse rate. This could be endorsed ...
The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
(Pharmacy, 2014 , Master Thesis)
The Na+/H+ exchanger-1 (NHE1) is a ubiquitously expressed housekeeping glycoprotein that functions to regulate intracellular pH. Enhanced expression/activity of NHE1 has been implicated in cardiac hypertrophy (CH). Recently, ...
Exploring the Impact and Value of Collaborative Care Model in Diabetes Care at a Primary Healthcare Setting In Qatar
(Pharmacy, 2020 , Master Thesis)
Background: Diabetes mellitus (DM) is one of the top health priorities in Qatar
due to its high prevalence and negative health consequences. The current prevalence of
DM in Qatar is 15.5%, which is projected to increase ...
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
(Pharmacy, 2020 , Master Thesis)
Poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery
systems and gene transfection as drug carriers. They also exert several biological effects
including modulating gene expression and interfering with ...
Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress
(Pharmacy, 2015 , Master Thesis)
Background: Endoplasmic reticulum (ER) is the chief organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease (CKD). Thus, there is ...
Medication-Related Burden among Patients with Chronic Disease Conditions: Perspectives of Patients attending Non-Communicable Disease Clinics in a Primary Healthcare Setting in Qatar
(Pharmacy, 2017 , Master Thesis)
This study aimed to adapt a medication-related burden instrument, the Living with Medicines Questionnaire (LMQ), into the Arabic context, report the psychometric properties of the Arabic version, and assess the burden ...
EVALUATION OF A CUMULATIVE EXIT-FROM-DEGREE OBJECTIVE STRUCTURED CLINICAL EXAMINATION (OSCE) IN A GULF CONTEXT
(Pharmacy, 2016 , Master Thesis)
This study aimed to evaluate the psychometric properties of the 2nd iteration of an Objective Structured Clinical Examination (OSCE) for graduating pharmacy students in Qatar. A secondary objective of this study was to ...
SUCCINYLATED CURCUMIN LOADED IN MANNOSYLATED CHITOSAN NANOPARTICLES FOR COLON CANCER THERAPY
(Pharmacy, 06-2 , Master Thesis)
Colon cancer (CRC) is the second leading cause of death and the third most diagnosed type worldwide. Although curcumin (CUR) has potent anticancer activity, it suffers from low solubility, bioavailability, and instability. ...
Nano Liposomal Formulation for A Novel Chalcone Compound as A Potential Anticancer Delivery System for Triple-Negative Breast Cancer
(Pharmacy, 2024 , Master Thesis)
Triple negative breast cancer is the most aggressive type of breast malignancy accounting for 15-20% of all breast cancer cases. Treatment of TNBC remains limited, with a high risk of relapse and metastasis to other organs. ...