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COMMUNITY PHARMACISTS' SELF-PERCEIVED COMPETENCY, AND ENABLERS, AND BARRIERS TOWARDS THE MANAGEMENT OF COMMON MINOR AILMENTS IN QATAR
(Pharmacy, 2021 , Master Thesis)
The study aimed to assess community pharmacists' self-perceived competency, and enablers and barriers towards managing common minor ailments in Qatar, and its predictors. A cross-sectional study, with pretested questionnaires, ...
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
(Pharmacy, 2021 , Dissertation)
The aim of this Ph.D. was to evaluate the periprocedural anticoagulation management of patients receiving warfarin in Qatar clinically and economically. In addition, exploring the clinical and economic impact of genetic ...
SUCCINYLATED CURCUMIN LOADED IN MANNOSYLATED CHITOSAN NANOPARTICLES FOR COLON CANCER THERAPY
(Pharmacy, 06-2 , Master Thesis)
Colon cancer (CRC) is the second leading cause of death and the third most diagnosed type worldwide. Although curcumin (CUR) has potent anticancer activity, it suffers from low solubility, bioavailability, and instability. ...
THE EFFECT OF NATURAL AND SYNTHETIC COMPOUNDS ON COLORECTAL CANCER: IN VITRO AND IN VIVO STUDIES
(Pharmacy, 06-2 , Master Thesis)
Colorectal cancer (CRC) is one of the deadliest malignancies in the world. Despite improved treatment, CRC incidence and mortality rates have been increasing lately. Current conventional therapies are associated with severe ...
ANTICANCER EFFECTS OF MODIFIED CITRUS PECTIN AND CURCUMIN IN CHITOSAN NANOPARTICLES ON COLON CANCER
(Pharmacy, 06-2 , Master Thesis)
We aimed to study the influence of stirring effect while modifying citrus pectin
(CP), in addition to create a combination of curcumin in chitosan-modified citrus pectin
(CCM-NPs) nanoparticles, along with Galectin-3 in ...
IMPACT OF SGLT2 INHIBITORS ON CKD PROGRESSION IN DIABETIC PATIENTS IN QATAR A RETROSPECTIVE COHORT STUDY
(Pharmacy, 2023 , Master Thesis)
Background: The risk of end-stage renal disease rises is based on the estimated glomerular filtration rate (eGFR) reduction. Even though multiple large-scale clinical trials have demonstrated the preventive benefits of ...
HYPERTENSION MANAGEMENT AND PRESCRIBING PRACTICES IN PRIMARY HEALTHCARE SETTINGS IN QATAR: A MULTI-METHODS
(Pharmacy, 2023 , Master Thesis)
Background: The use of antihypertensive medications controls blood pressure (BP) and reduces the incidence of complications. This study explored the prescribing patterns and trends of antihypertensive medications utilization, ...
EXPLORATION OF THE APPLICATION OF PHARMACOGENETICS IN THE MANAGEMENT OF DEPRESSION
(Pharmacy, 2023 , Master Thesis)
Genetic factors have been reported as playing an important role in the treatment efficacy of antidepressants (ADs). Studies report up to 55 % of patients experience AD treatment failure. The aim of this research was to ...
The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
(Pharmacy, 2014 , Master Thesis)
The Na+/H+ exchanger-1 (NHE1) is a ubiquitously expressed housekeeping glycoprotein that functions to regulate intracellular pH. Enhanced expression/activity of NHE1 has been implicated in cardiac hypertrophy (CH). Recently, ...
STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJURY
(Pharmacy, 2015 , Master Thesis)
Diabetic nephropathy (DN) is the leading cause of end stage renal disease, and one of the most serious microvascular complications of diabetes mellitus. Increase in the shift of glucose into the aldose reductase pathway ...