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المؤلفAugustine R.
المؤلفHasan, Anwarul
المؤلفPrimavera R.
المؤلفWilson R.J.
المؤلفThakor A.S.
المؤلفKevadiya B.D.
تاريخ الإتاحة2022-05-21T10:18:29Z
تاريخ النشر2020
اسم المنشورMaterials Today Communications
المصدرScopus
المعرّفhttp://dx.doi.org/10.1016/j.mtcomm.2020.101692
معرّف المصادر الموحدhttp://hdl.handle.net/10576/31289
الملخصThe utilization of nanomaterials in the biological and medical field is quickly progressing, particularly in areas where traditional diagnostics and treatment approaches have limited success. The success of nanomaterials in medical products such as biomedical implants, wound dressings and drug delivery systems rely upon their effective interaction between the extracellular matrix, cells, and intracellular components. Upon contact with mammalian cells, nanoparticles (NPs) begin to interact with the extracellular matrix, cell membrane, cytoplasmic proteins, nucleus, and other cellular organelles, which result in nanoparticle internalization and subsequent cellular responses. Such responses elicited by the mammalian cells as a result of the cell-nanomaterials interactions, both at the cellular and molecular level, are mainly determined by the morphological, chemical, and surface characteristics of the nanomaterials themselves. This review provides an overview of how such different attributes, such as chemical nature, size, shape, surface charge, topography, stiffness, and functional features of nanomaterials, influence the cell-nanomaterials interactions.
اللغةen
الناشرElsevier Ltd
الموضوعCell-nanoparticle interaction
charge
functional groups
mammalian cells
nanomaterials
shape
size
العنوانCellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components
النوعArticle
رقم المجلد25
dc.accessType Open Access


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