Medicine Research
Recent Submissions
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POST-TRANSLATIONAL MODIFICATIONS IN CANCER AND DIABETES
(2025 , Dissertation)Background: In Qatar, non-communicable diseases like cancer and diabetes are leading causes of mortality. Cancer is caused by various environmental and hereditary factors, with metastasis from the primary site being the ... -
VASCULAR REMODELING IN HYPERTENSION: IN-VITRO/ EX-VIVO MECHANICAL STRETCH-INDUCED ALTERATIONS AND OMICS ANALYSIS
(2024 , Dissertation)Hypertension, being a primary vasculature disorder, contributes significantly to premature death globally. Over the years, numerical figures have evidenced a dramatic increase in hypertension’s global prevalence, affecting ... -
INVESTIGATING THE MOLECULAR MECHANISMS OF SHEAR STRESS INDUCED ENDOTHELIAL DYSFUNCTION AND PROGRESSION OF ATHEROSCLEROSIS
(2024 , Dissertation)Background: Atherosclerotic vascular disease, such as coronary artery disease (CAD) and ischemic stroke is the leading cause of mortality and disability worldwide. Therefore, understanding the mechanisms underlying ... -
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
(2024 , Dissertation)Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. CBS is a pivotal enzyme whose activity is enhanced by the allosteric regulator S-adenosylmethionine ... -
Co-Presence and Cooperation of High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer
(2024 , Dissertation)The Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) are potent oncoviruses involved in the pathogenesis of various cancers like colorectal cancer. Further the cooperation between high risk (HR) types of HPV as well ... -
METABOLIC CHANGES AFTER SURGICAL SUBCUTANEOUS FAT REMOVAL
(2023 , Dissertation)Background: There is increasing demand for both surgical (SSFR) and nonsurgical (NSSFR) subcutaneous fat removal procedures for achieving immediate improvements in physical appearance. However, their metabolic effects ... -
Vitamin D Immune Modulatory Effect on the Anti-inflammatory potential of HDL Associated Proteins
(2023 , Dissertation)Introduction: Vitamin D deficiency is highly prevalent in Qatar. Vitamin D exerts immune-modulatory effects leading to reduced inflammation. Therefore, vitamin D deficiency is associated with increased subclinical inflammation. ... -
DEVELOPMENT OF A PROBLEM AND ATTRIBUTES BASED DIABETES SELF-MANAGEMENT (PARADIGM) INTERVENTION
(2022 , Dissertation)Background: Type 2 diabetes mellitus (T2D), is a growing pandemic across the world. T2D requires a comprehensive diabetes self-management (DSM) skills in addition to medications. It is still unclear what interventions can ...
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