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السجلات المعروضة 10542 -- 10561 من 17691
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Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region
( Elsevier , 2022 , Article)Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide, particularly among children under five years in underdeveloped countries. Most acute gastroenteritis (AGE) cases are attributed to viral ... -
Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
( Austin Publishing Group , 2021 , Article)Camel Milk (CM) and Camel Urine (CU) is a traditional practice in the Middle East and other countries as an alternative treatment against cancer. We hypothesized that a combination of CM and CU (CM+CU), used at ... -
Molecular Evidence of Breast Cancer Cell Proliferation Inhibition by a Combination of Selected Qatari Medicinal Plants Crude Extracts
( MDPI , 2023 , Article): Breast cancer (BC) is the most common malignancy, and conventional medicine has failed to establish efficient treatment modalities. Conventional medicine failed due to lack of knowledge of the mechanisms that underpin ... -
Molecular identification and biocontrol of ochratoxigenic fungi and ochratoxin A in animal feed marketed in the state of Qatar
( Elsevier Ltd , 2023 , Article)Ochratoxin A (OTA) is a toxic fungal metabolite produced by some Aspergillus and Penicillium species. This work was designed to explore the presence of OTA and ochratoxigenic fungi in feed grains marketed in Qatar and their ... -
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
( Frontiers Media S.A. , 2020 , Article)In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV ... -
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.
( Elsevier , 2019 , Article)The G2019S substitution in the Leucine-rich repeat kinase 2 (LRRK2) is significantly associated with Parkinson's disease (PD). This substitution was identified in both familial and sporadic forms of PD with a higher ... -
Molecular investigation of waterborne protozoan contamination using marine Demospongiae
( Elsevier , 2024 , Article)Sponges play important role within aquatic ecosystems due to their diverse abilities including filter-based feeding mechanisms. Hence, this study evaluated the potential use of sponges as ecological biomonitors for water ... -
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
( hindawi , 2020 , Article)Hypertension induces vascular hypertrophy, which changes blood vessels structurally and functionally, leading to reduced tissue perfusion and further hypertension. It is also associated with dysregulated levels of the ... -
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
( MDPI , 2020 , Article Review)Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ... -
Molecular Mechanisms of Peritoneal Dialysis–Induced Microvascular Vasodilation
( Peritoneal Dialysis Bulletin , 2014 , Article)Peritoneal dialysis (PD) solutions dilate microvessels by undefined mechanisms. This vasodilation directly affects ultrafiltration and solute exchange during a PD dwell and is thought to account for the variable mass ... -
Molecular Mechanisms Underpinning Microparticle-Mediated Cellular Injury in Cardiovascular Complications Associated with Diabetes.
( Hindawi , 2019 , Article)Microparticles (MPs) are small vesicles shed from the cytoplasmic membrane of healthy, activated, or apoptotic cells. MPs are very heterogeneous in size (100-1,000 nm), and they harbor proteins and surface antigens specific ... -
Molecular Modeling Guided Drug Designing for the Therapeutic Treatment of Rheumatoid Arthritis
( Hindawi , 2022 , Article)Rheumatoid arthritis (RA) is a systemic inflammatory disorder that can cause destructive joint disease, significant disability, and increased mortality. RA is the most frequent of all chronic inflammatory joint diseases, ... -
Molecular phylogenetic analysis of nuclear genes suggests a Cenozoic over-water dispersal origin for the Cuban solenodon
( Nature Publishing Group , 2016 , Article)The Cuban solenodon (Solenodon cubanus) is one of the most enigmatic mammals and is an extremely rare species with a distribution limited to a small part of the island of Cuba. Despite its rarity, in 2012 seven individuals ... -
Molecular phylogeny of Qatari date palm genotypes using Simple Sequence Repeats markers
( Asian Network for Scientific Information , 2009 , Article)The objectives of the present study is to analyze the genetic diversity among 15 different cultivars of date palm at the experimental farm of Qatar University using Simple Sequence Repeat (SSR) markers and find out the ... -
Molecular Profiling of Clear Cell Carcinoma of the Breast Reveals Novel Targetable Biomarkers
( Springer Nature , 2020 , Conference Paper)Background: Although clear cell morphology may be seen in various subtypes of breast cancer, a pure variant of clear cell carcinoma (usually glycogen-rich) is a very rare primary breast malignancy. It is characterized by ... -
Molecular profiling of the metaplastic spindle cell carcinoma of the breast reveals potentially targetable biomarkers
( Elsevier , 2020 , Article)IntroductionSpindle cell carcinoma is a rare subtype of metaplastic breast cancer (MBC), with triple-negative (TNBC: ER-/PR-/Her2-) phenotype. It is associated with a marked resistance to conventional chemotherapy and has ... -
Molecular Profiling Reveals Limited Targetable Biomarkers in Neuroendocrine Carcinoma of the Cervix.
( Lippincott, Williams & Wilkins , 2020 , Article)Neuroendocrine carcinoma of the cervix (NEC) is a rare and highly aggressive cervical malignancy. Given that no targeted therapy has been approved specifically to NEC, we investigated the presence of novel, potentially ... -
Molecular profiling reveals novel targetable biomarkers in neuroendocrine carcinoma of the uterine cervix
( Oxford University Press , 2019 , Conference Paper)Background Neuroendocrine carcinoma of the uterine cervix (NEC) is a rare cervical malignancy, accounting for 0.9% of all cervical carcinomas. Cervical NEC is a high-grade cancer with an aggressive clinical course and ... -
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives
( Tabriz University of Medical Sciences , 2023 , Article)Introduction: The anticancer and anti-inflammatory activities of a novel series of eleven pyrimido[1,2-b]pyridazin-2-one analogues substituted at position 7 were assessed in the current study. Methods: The physicochemical ... -
Molecular Property Clustering Techniques
( Elsevier B.V. , 2016 , Book chapter)In this work, systematic property clustering methods for molecular design are described. Group contribution first-order estimation methods are coupled with property clustering methods to define the targets of the property ...
