Browsing Faculty Contributions by Subject "cardiovascular disease"
Now showing items 1-20 of 35
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Association between Grain and Legume Consumption and the Risk of Coronary Artery Obstruction among Jordanians Based on Angiography Results
( Korean Society of Food Science and Nutrition , 2021 , Article)Accumulating evidence suggests that consumption of whole grains and legumes is associated with reduced risk of cardiovascular disease (CVD), whereas the risk is increased by consuming refined grains and cereals. This study ... -
C-peptide in diabetes: A player in a dual hormone disorder?
( Wiley-Blackwell , 2024 , Article)C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ... -
The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome-The NHANES Survey during 2005-2016.
( MDPI , 2022 , Article)The study aimed to compare the predictive value of the Circadian Syndrome (CircS) and Metabolic Syndrome (MetS) for cardiovascular disease (CVD). We used data of 12,156 adults aged ≥20 years who attended National Health ... -
The circadian syndrome predicts cardiovascular disease better than metabolic syndrome in Chinese adults.
( Wiley , 2020 , Article)To compare the predictive value of the circadian syndrome (CircS) and Metabolic syndrome (MetS) for cardiovascular disease. We used the data of 9360 Chinese adults aged ≥40 years from the 2011 China Health and Retirement ... -
Consequences of a Great Crisis on Chronic Diseases: How Childhood Exposures May Shape Future Health
( John Wiley and Sons Inc , 2021 , Article)[No abstract available] -
Cost-Effectiveness of Empagliflozin and Metformin Combination Versus Standard Care as First-Line Therapy in Patients With Type 2 Diabetes Mellitus
( Elsevier , 2022 , Article)ObjectiveSodium-glucose cotransporter 2 inhibitors have been shown to reduce cardiovascular events but are currently not used as the first-line therapy. This study was conducted to evaluate the cost-effectiveness of ... -
Early life exposure to 1959-1961 Chinese famine exacerbates association between diabetes and cardiovascular disease.
( Wiley , 2019 , Article)We aimed to assess whether early life exposure to the Chinese famine (1959-1961) modifies the association between type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) in adulthood. Data from 4247 adults born ... -
The effect of nuts consumption on circulating oxidized low-density lipoproteins: A systematic review and meta-analysis of randomized controlled trials.
( Wiley , 2023 , Article Review)This systematic review and meta-analysis evaluated the effect of nuts in decreasing circulating levels of oxidized low-density lipoproteins (ox-LDL). A literature search was performed of major electronic databases ... -
Elucidating the chemical profile and biological studies of Verbascum diversifolium Hochst. extracts
( Frontiers Media SA , 2024 , Article)The present study was designed to evaluate the chemical composition, antioxidant, enzyme inhibition and cytotoxic properties of different extracts from aerial parts of V. diversifolium (family Scrophulariaceae), a plant ... -
Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival.
( Frontiers Media , 2020 , Article)Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular abnormalities. Among these EVs, microparticles (MPs) are vesicles directly ... -
Evaluation of cardiovascular risk in adult psychiatric outpatients in Qatar using two risk assessment tools
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Introduction: Individuals with serious mental illness (SMI) experience premature death, likely due to increased rates of obesity and cardiovascular disease (CVD). This study was conducted to estimate the CVD risk in a ... -
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
( Portland Press Ltd , 2020 , Article Review)Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ... -
G protein estrogen receptor as a potential therapeutic target in Raynaud’s phenomenon
( Frontiers Media , 2022 , Article)Exaggerated cold-induced vasoconstriction can precipitate a pathogenesis called Raynaud’s phenomenon (RP). Interestingly, RP is significantly more prevalent in females than age-matched men, highlighting the potential ... -
The impact of health status, diet and lifestyle on non-alcoholic fatty liver disease: Narrative review
( Wiley , 2022 , Article Review)Non-alcoholic fatty liver disease (NAFLD) is defined as the abnormal accumulation of triglycerides in the liver. NAFLD has a global prevalence of almost 30%, while incidence is rising with increasing levels of obesity, ... -
Impact of the MIF -173G/C variant on cardiovascular disease risk: a meta-analysis of 9,047 participants
( Frontiers Media SA , 2024 , Article Review)Introduction: Many factors contribute to the risk of cardiovascular disease (CVD), an umbrella term for several different heart diseases, including inflammation. Macrophage migration inhibitory factor (MIF) is an important ... -
Infection with Helicobacter pylori may predispose to atherosclerosis: role of inflammation and thickening of intima-media of carotid arteries
( Frontiers Media , 2023 , Article Review)Atherosclerosis is a major instigator of cardiovascular disease (CVD) and a main cause of global morbidity and mortality. The high prevalence of CVD calls for urgent attention to possible preventive measures in order to ... -
Inflammation and hypertension: Underlying mechanisms and emerging understandings
( wiley online library , 2023 , Article Review)Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ... -
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
( Springer Nature , 2023 , Article)There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ... -
Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction
( MDPI , 2020 , Article)Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at ... -
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
( Taylor and Francis Ltd , 2020 , Article)Objectives: Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize ...