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Recent advances in functional nanostructures as cancer photothermal therapy.
(
Dove Medical Press
, 2018 , Article Review)
Being a non-invasive and relatively safe technique, photothermal therapy has attracted a lot of interest in the cancer treatment field. Recently, nanostructure technology has entered the forefront of cancer therapy owing ...
The march of pluripotent stem cells in cardiovascular regenerative medicine.
(
BMC
, 2018 , Article Review)
Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and mortality. Heart failure remains a major contributor to this mortality. Despite major therapeutic advances over the past decades, a ...
Polymeric Micelles of Biodegradable Diblock Copolymers: Enhanced Encapsulation of Hydrophobic Drugs
(
MDPI
, 2018 , Article Review)
Polymeric micelles are potentially efficient in encapsulating and performing the controlled release of various hydrophobic drug molecules. Understanding the fundamental physicochemical properties behind drug–polymer systems ...
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
(
BMC
, 2018 , Article Review)
Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ...
Recent advances in applications of active constituents of selected medicinal plants of dhofar, sultanate of oman
(
Innovare Academics Sciences Pvt. Ltd
, 2018 , Article Review)
The Dhofar region of Oman is extremely opulent in plant biodiversity in comparison to other parts of the country. Most of the cultivated, medicinal and wild plants of the region are available in the mountainous side and ...
The role of gene gjb2 and connexin 26 in hearing impairment
(
Palladin Institute of Biochemistry of the NASU
, 2018 , Article Review)
Gap Junction Beta 2 (GJB2) gene mutations are the leading causes of hereditary hearing impairment. This gene encodes various gap junction proteins such as connexin 26 (Cx26), which facilitate K+ homeostasis inside the ...
Current status of tissue engineering in the management of severe hypospadias
(
Frontiers Media S.A.
, 2018 , Article Review)
Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ...
Cisplatin based therapy: The role of the mitogen activated protein kinase signaling pathway
(
BioMed Central Ltd.
, 2018 , Article Review)
Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced ...
Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
(
Taylor and Francis Ltd
, 2018 , Article Review)
Introduction: Exploration in the field of epigenetics has revealed the diverse roles of the protein arginine methyltransferase (PRMT) family of proteins in multiple disease states. These findings have led to the development ...
Digenic inheritance and genetic modifiers
(
Blackwell Publishing Ltd
, 2018 , Article Review)
Digenic inheritance (DI) concerns pathologies with the simplest form of multigenic etiology, implicating more than 1 gene (and perhaps the environment). True DI is when biallelic or even triallelic mutations in 2 distinct ...