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Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
(
MDPI
, 2020 , Article Review)
Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...
The Interplay Between Diet and the Epigenome in the Pathogenesis of Type-1 Diabetes
(
Frontiers
, 2021 , Article Review)
The autoimmune disease, Type 1 Diabetes Mellitus (T1DM), results in the destruction of pancreatic β-cells, and the International Diabetes Federation reports that its incidence is increasing worldwide. T1DM is a complex ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
Information, Thermodynamics and Life: A Narrative Review
(
MDPI
, 2021 , Article Review)
Information is probably one of the most difficult physical quantities to comprehend. This applies not only to the very definition of information, but also to the physical entity of information, meaning how can it be ...
An overview of brine management: Emerging desalination technologies, life cycle assessment, and metal recovery methodologies
(
Elsevier
, 2021 , Article Review)
This study examines which management methods are the most recent and advanced in managing rejected brine generated from desalination plants. It also provides up-to-date information regarding the most adequate technologies ...
The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap
(
Frontiers Media
, 2021 , Article Review)
Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ...
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
Growing Burden of Hypertension in China: Causes, Challenges, and Opportunities
(
Chinese Center for Disease Control and Prevention (China CDC)
, 2020 , Article Review)
Cardiovascular disease (CVD) is the leading cause of
death in China, and an estimated 290 million
individuals are affected by CVD in China (1).
Hypertension is the most important risk factor of
CVD (2). Good control ...