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Now showing items 11-20 of 28
Polymeric-based microneedle arrays as potential platforms in the development of drugs delivery systems
(
Elsevier B.V.
, 2020 , Article)
Background: Microscopic patches as quite promising platforms in transdermal drug delivery suffer from conventional injections. In other hand, a wide range of pharmacokinetics, ranging from fast oral administration to ...
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy ...
Enhancement of gemcitabine against pancreatic cancer by loading in mesoporous silica vesicles
(
Elsevier B.V.
, 2017 , Article)
Gemcitabine (Gem) is currently the first-line chemotherapeutic drug in management of pancreatic cancer, however the therapeutic efficacy of Gem is limited due to its short half-life and poor cell membrane permeability. ...
Mucoadhesive chitosan derivatives as novel drug carriers
(
Bentham Science Publishers B.V.
, 2015 , Article)
Chitosan on its own is a well-established natural polymer and is widely regarded as a biodegradable, biocompatible and nontoxic material for drug delivery applications. Although unmodified chitosan has some mucoadhesive ...
Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy
(
Elsevier B.V.
, 2019 , Article Review)
Over the past two decades, the development of plasmonic nanoparticle (NPs), especially gold (Au) NPs, is being pursued more seriously in the medical fields such as imaging, drug delivery, and theranostic systems. However, ...
Nanoparticles: Attractive tools to treat colorectal cancer
(
Elsevier
, 2022 , Article)
Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Despite the notable advances achieved over the last few decades, CRC remains a hard-to-treat deadly disease in many patients. This ...
Development of biopolymeric hybrid scaffold-based on aac/go/nhap/tio2 nanocomposite for bone tissue engineering: In-vitro analysis
(
MDPI AG
, 2021 , Article)
Bone tissue engineering is an advanced field for treatment of fractured bones to re-store/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone ...
Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers
(
Elsevier
, 2021 , Article)
Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect. Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer protection from degradation and enhance ...
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
(
Elsevier B.V.
, 2018 , Article Review)
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ...
A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
(
Elsevier B.V.
, 2016 , Article)
Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ...