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Targeting HER2 expression in cancer: New drugs and new indications.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2020 , Article)
Functional activation of human epidermal growth factor receptor 2 (HER2) has been shown to strongly promote carcinogenesis, leading to the investigation of HER2-directed agents in cancers with HER2 genomic alterations. ...
Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres
(
Nature Research
, 2020 , Article)
The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ...
The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.
(
Taylor and Francis
, 2020 , Article)
High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein-Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal. ...
Dietary inflammatory index and odds of breast cancer: A case-control study
(
Wiley
, 2021 , Article)
Breast cancer (BrCA) is one of the most commonly diagnosed cancers and is the leading cause of cancer deaths in women worldwide. This study aimed to examine the association between the dietary inflammatory index (DII®) and ...
Editorial: EBV-Associated Carcinomas: Presence, Role, and Prevention Strategies.
(
Frontiers Media
, 2019 , Other)
This special issue addresses an important topic related to the role of Epstein-Barr virus (EBV) in human carcinomas initiation and progression, which is one of the most common viral infections worldwide. Today, the ...
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
(
Dove Medical Press
, 2020 , Article)
Venetoclax (VCX) is a selective BCL-2 inhibitor approved for the treatment of leukemia and lymphoma. However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic ...
Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
(
Taylor & Francis
, 2016 , Article)
ABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we ...
Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets.
(
MDPI
, 2020 , Article)
Breast cancer is one of the most prevalent diseases among women worldwide and is highly associated with cancer-related mortality. Of the four major molecular subtypes, HER2-positive and triple-negative breast cancer (TNBC) ...
Psychosocial Aspects of Female Breast Cancer in the Middle East and North Africa.
(
MDPI
, 2020 , Article)
Breast cancer, the most common cancer among women in the Middle East and North Africa (MENA) region, is associated with social and psychological implications deriving from women's socio-cultural contexts. Examining 74 ...
Carnosol Induces p38-Mediated ER Stress Response and Autophagy in Human Breast Cancer Cells
(
Frontiers
, 2022 , Article)
We recently reported that carnosol induces ROS-dependent autophagy and apoptosis in breast cancer cells. We also reported that carnosol inhibits breast cancer cell migration, invasion, and in ovo tumor growth, as well as ...