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Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
(
Wiley
, 2020 , Article)
© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ...
MXene Nanosheets May Induce Toxic Effect on the Early Stage of Embryogenesis.
(
American Scientific Publishers
, 2020 , Article)
MXene (Ti₃C₂T), as a novel 2D material, has produced a great interest due to its promising properties in biomedical applications, nevertheless, there is a lack of studies dedicated to investigate the possible toxic effect ...
Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities
(
Elsevier B.V.
, 2021 , Article Review)
The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. ...
Natural halloysite nanotubes /chitosan based bio-nanocomposite for delivering norfloxacin, an anti-microbial agent in sustained release manner
(
Elsevier B.V.
, 2020 , Article)
Applying nanotechnology to deliver drug could result in several benefits such as prolong duration of action, enhancement in overall bioavailability, targeting to specific site, low initial loading dose require, systemic ...
Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
(
Elsevier B.V.
, 2021 , Article)
Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ...
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
(
Elsevier B.V.
, 2020 , Article)
Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
(
Elsevier B.V.
, 2020 , Article)
The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ...
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical ...
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
(
Elsevier B.V.
, 2020 , Article)
Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ...
Antioxidant properties of gold nanozyme: A review
(
Elsevier B.V.
, 2020 , Article)
AuNPs with enzyme-like features have received strong attention in different areas, although limited data is available in literature on their biological/industrial functions. NPs especially Au counterparts have been shown ...