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The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells
(
Qatar University Press
, 2021 , Poster)
Introduction: Both Dasatinib (DA), a tyrosine kinase inhibitor that is used for targeted cancer therapy, and programmed death-ligand 1 (PD-1/PD-L1) inhibitor that is an immune checkpoint therapy, play a vital role in the ...
Comparison of demographic and clinical characteristics in distinguishing testicular torsion from torsion of the appendix testis: A single-center retrospective study
(
Elsevier
, 2022 , Article)
Testicular torsion (TT) is an emergency requiring a prompt diagnosis and surgery to avoid irreversible changes and a complete loss of testis. The present study aimed to identify potential factors that may predict a testicular ...
Role and Significance of c-KIT Receptor Tyrosine Kinase in Cancer: A Review.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2022 , Article Review)
c-kit is a classical proto-oncogene that encodes a receptor tyrosine kinase (RTK) that responds to stem cell factor (SCF). C-KIT signaling is a critical regulator of cell proliferation, survival, and migration and is ...
An infant with ankyloblepharon filiforme adnatum associated with a cleft lip and palate: A case report
(
Elsevier
, 2022 , Other)
Ankyloblepharon filiform adnatum (AFA) is a rare but potentially ambylogenic congenital anomaly characterized by a partial or complete fusion of the eyelid margins.1 Although AFA has been reported as an isolated finding, ...
PD-L1 testing by immunohistochemistry in Immuno-Oncology.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2022 , Article Review)
Immunotherapy, based on immune checkpoint inhibitors targeting the Programmed cell death ligand 1 (PD-L1) and/or Programmed Death Receptor 1 (PD-1), has substantially improved the outcomes of patients with various cancers. ...
Alpha-methylacyl-CoA Racemase (AMACR) Protein is Upregulated in Early Proliferative Lesions of the Breast Irrespective of Apocrine Differentiation
(
Elsevier
, 2022 , Other)
Alpha-methylacyl-CoA racemase (AMACR/P504S) is a mitochondrial and peroxisomal enzyme involved in the branched-chain fatty acid and bile acid metabolism. AMACR is a useful diagnostic biomarker for prostate carcinomas and ...
Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl
(
Elsevier
, 2022 , Article)
Non-operative treatment of high-grade renal trauma in hemodynamically stable children is gaining increasing acceptance nowadays. However, the management of isolated grade IV injuries, particularly those with complete renal ...
A Giant Polypoid Gastric Heterotopia of the Ileum as a Cause of Intussusception in an Adolescent.
(
Department of Medical Sciences, Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina
, 2022 , Article)
Histopathological examination confirmed a well-demarcated polyp, lined by a foveolar-type epithelium, with all the elements found in the gastric mucosa, and a well-developed gastric gland. No dysplasia or malignancy was ...
Epidemiologic and clinical characteristics of selected congenital anomalies at the largest Bosnian pediatric surgery tertiary center
(
Lippincott, Williams & Wilkins
, 2022 , Article)
Congenital anomalies (CA) are any abnormality present at birth, either structural or functional, that may potentially affect an infant's health, development, and/or survival. There is a paucity of studies on clinical ...
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
(
Frontiers Media
, 2022 , Article)
Immune checkpoint blockade (ICB)-based therapy is revolutionizing cancer treatment by fostering successful immune surveillance and effector cell responses against various types of cancers. However, patients with HER2+ ...