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Molecular profiling of the metaplastic spindle cell carcinoma of the breast reveals potentially targetable biomarkers
(
Elsevier
, 2020 , Article)
IntroductionSpindle cell carcinoma is a rare subtype of metaplastic breast cancer (MBC), with triple-negative (TNBC: ER-/PR-/Her2-) phenotype. It is associated with a marked resistance to conventional chemotherapy and has ...
Women's Health and Well-Being in the United Nations Sustainable Development Goals: A Narrative Review of Achievements and Gaps in the Gulf States.
(
MDPI
, 2020 , Article)
In 2014, United Nations member states proposed a set of sustainable development goals (SDGs) to help further the millennium development goals that they had proposed in New York in 2000. Of these 13 SDGs, Goal 3 (i.e., SDG ...
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
(
Springer
, 2020 , Article)
Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ...
Adiposity indicators as cardiometabolic risk predictors in adults from country with high burden of obesity
(
Dove Medical Press
, 2020 , Article)
Background : In Qatar more than 70% 0f the adults are overweight and obese. Different adiposity assessment methods have been proposed to identify individuals at cardio-metabolic risk.
Purpose : This study aimed to compare ...
Bowel Dilatation on Initial Plane Abdominal Radiography May Help to Assess the Severity of Necrotizing Enterocolitis in Preterm Infants.
(
MDPI
, 2020 , Article)
Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency associated with prematurity. Timely diagnosis and adequate treatment are crucial to reduce the morbidity and mortality of the ...
Thymoquinone Suppresses Cell Proliferation and Enhances Apoptosis of HL60 Leukemia Cells through Re-Expression of JAK/STAT Negative Regulators.
(
West Asia Organization for Cancer Prevention (WAOCP)
, 2021 , Article)
The natural compound, thymoquinone (TQ) has demonstrated potential anticancer properties in inhibiting cell proliferation and promoting apoptosis in myeloid leukemia cells, breast cancer cells, and others. However, the ...
Developing an indicator system for a healthy City: Taking an urban area as a pilot
(
Dove Medical Press
, 2020 , Article)
Purpose: The Healthy Cities Project is an important strategy for global health. This study aimed to develop a scientific and appropriate indicator system for the evaluation of a Healthy City in Chongqing, China. Methods: ...
The vascular glycocalyx is not a mechanosensor in conduit arteries in the anesthetized pig.
(
PeerJ
, 2020 , Article)
The role of the glycocalyx as the endothelial sensor of an increase in blood flow was assessed in the iliac artery in vivo. Acetylcholine-induced flow mediated dilation was evaluated before and after vascular glycocalyx ...
Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar
(
Springer
, 2021 , Article)
Acute gastroenteritis (AGE) remains a major cause of diarrhea in developing and developed countries. Rotavirus (RV) is a leading cause of severe pediatric diarrhea worldwide. Here we report on the prevalence of circulating ...
الحوار في القرآن والسنة وموقف الإسلام من غير المسلمين
(
مجمع البحوث الاسلامية - الجامعة الإسلامية العالمية
, 2020 , Article)
تعيش الأمة الإسلامية حالة عصيبة من الزمن، اختلط فيها الواقع بالخيال، الأمل باليأس، ومع تفرق أبناء الأمة ظهرت الحاجة للتقريب بين المسلمين، فضلا عن ضرورة الوحدة، ولكن هذا الأمر لا يحدث إلا بعد تحديد المشكلة، من أجل تحديد ...