Search
Now showing items 1-6 of 6
Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
(
Dove Medical Press Ltd.
, 2019 , Article)
Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ...
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
(
Elsevier B.V.
, 2019 , Article)
In this study, we formulated silymarin-HSA nanoplex and assayed its ability to reduce LPS-induced toxicity in vitro and in vivo. Silymarin molecules were encapsulated into HSA nanoplex and the loading efficiency and ...
Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy
(
Elsevier B.V.
, 2019 , Article Review)
Over the past two decades, the development of plasmonic nanoparticle (NPs), especially gold (Au) NPs, is being pursued more seriously in the medical fields such as imaging, drug delivery, and theranostic systems. However, ...
Albumin binding, antioxidant and antibacterial effects of cerium oxide nanoparticles
(
Elsevier B.V.
, 2019 , Article)
Herein, the interaction of CeO2 NPs with HSA was explored by fluorescence, CD, UV–vis and molecular docking studies. Afterwards, the antioxidant activity of CeO2 NPs against H2O2-induced oxidative stress in BM-MSCs were ...
The effect of aluminum oxide on red blood cell integrity and hemoglobin structure at nanoscale
(
Elsevier B.V.
, 2019 , Article)
Herein, we explored the interaction of Al2O3 NPs with RBCs and Hb to determine the effect of Al2O3 NPs on hemolytic activity and Hb denaturation. The percentage of hemolysis of extracts and direct contact assays triggered ...
Vitamin K1 as a potential molecule for reducing single-walled carbon nanotubes-stimulated �-synuclein structural changes and cytotoxicity
(
Dove Medical Press Ltd.
, 2019 , Article)
Aims: Different kinds of vitamins can be used as promising candidates to mitigate the structural changes of proteins and associated cytotoxicity stimulated by NPs. Therefore, the structural changes of �-syn molecules and ...