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Targeting dopaminergic system for treating nicotine dependence
(
Bentham Science Publishers B.V.
, 2016 , Article)
Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...