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MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes.
(
MDPI
, 2019 , Article)
Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), ...
Abdominal Fat Is Directly Associated With Inflammation In PersonsWith Type-2 Diabetes Regardless Of Glycemic Control – A Jordanian Study
(2019 , Article)
Background and aim: Systemic inflammation is related to the progression of complications
associated with diabetes. This study aimed to investigate the association between
general and abdominal obesity and inflammation ...
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
(
MDPI
, 2021 , Article)
Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic ...
Readability and Comprehensibility of Patient Information Leaflets for Antidiabetic Medications in Qatar
(
SAGE Publications Inc.
, 2017 , Article)
Background:The readability and comprehensibility of the patient information leaflets (PILs) provided with antidiabetic medications are of questionable standards; this issue negatively affects adherence to drug therapy, ...
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
(
Frontiers Media
, 2019 , Article Review)
Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ...
Assessment of the Role of Serum 25-Hydroxy Vitamin D Level on Coronary Heart Disease Risk With Stratification Among Patients With Type 2 Diabetes Mellitus
(
SAGE Publications
, 2020 , Article)
© The Author(s) 2020. We investigated the role of vitamin D on glycemic regulation and cardiac complications in patients with type 2 diabetes mellitus (T2DM). A total of 1139 patients (49.3% males vs 50.7% females) were ...
The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.
(
MDPI
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Muscle Strength and Glycaemic Control among Patients with Type 2 Diabetes.
(
MDPI
, 2020 , Article)
Poor glycaemic control is associated with chronic life-threatening complications. This cross-sectional study examined whether there is an association between handgrip strength and glycaemic control among patients with ...
Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction
(
MDPI
, 2020 , Article)
Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at ...
Chinese Famine and the diabetes mellitus epidemic.
(
Nature Research
, 2019 , Article)
We thank Li et al. (The effect of the Chinese Famine on type 2 diabetes mellitus epidemics. Nat. Rev. Endocrinol. 15, 313–314 (2019))1 for their interest in our paper and agree that some studies on the association between ...