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Unusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides
(
Taylor & Francis
, 2017 , Article)
A one-pot, three-component protocol for the synthesis of novel five-membered thiazole ring bonded to two hydrazone motifs is described. The acid-catalyzed reaction of one equivalent of thiocarbohydrazide, two equivalents ...
Cardiovascular disease in the Eastern Mediterranean region: epidemiology and risk factor burden
(
Nature Publishing Group
, 2017 , Article Review)
The Eastern Mediterranean region (EMR) comprises 22 countries or territories spanning from Morocco in the west to Pakistan in the east, and contains a population of almost 600 million people. Like many other developing ...
Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
(
Hindawi
, 2017 , Article)
Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, ...
PopPAnTe: population and pedigree association testing for quantitative data.
(
BioMed Central
, 2017 , Article)
Family-based designs, from twin studies to isolated populations with their complex genealogical data, are a valuable resource for genetic studies of heritable molecular biomarkers. Existing software for family-based studies ...
Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis
(
Elsevier
, 2017 , Article)
Background Soil-transmitted helminth infections are a major global health issue, causing substantial morbidity in the world's poorest populations. Regular delivery of anthelmintic drugs is the mainstay for global ...
Upper Versus Lower Gastrointestinal Delivery for Transplantation of Fecal Microbiota in Recurrent or Refractory Clostridium difficile Infection: A Collaborative Analysis of Individual Patient Data From 14 Studies
(
Wolters Kluwer
, 2017 , Article)
The aim of this study was to compare upper gastrointestinal (UGI) versus lower gastrointestinal (LGI) delivery routes of fecal microbiota transplantation (FMT) for refractory or recurrent/relapsing Clostridium difficile ...
Effect of Immediate Administration of Antibiotics in Patients With Sepsis in Tertiary Care: A Systematic Review and Meta-analysis
(
Elsevier
, 2017 , Article)
Purpose The goal of this review was to synthesize existing evidence regarding outcomes (mortality) for patients who present to the emergency department, are administered antibiotics immediately (within 1 hour) or later (>1 ...
Total temporomandibular joint replacement prostheses: a systematic review and bias-adjusted meta-analysis
(
Elsevier
, 2017 , Article)
The aim of the present study was to determine which prosthesis has resulted in the best outcomes after total temporomandibular joint replacement (TMJR). A comprehensive electronic search was undertaken in September 2015. ...
Chronic probiotic supplementation with or without glutamine does not influence the eHsp72 response to a multi-day ultra-endurance exercise event.
(
NRC Research Press
, 2017 , Article)
Probiotic and glutamine supplementation increases tissue Hsp72, but their influence on extracellular Hsp72 (eHsp72) has not been investigated. The aim of this study was to investigate the effect of chronic probiotic ...
Reaction kinetics of carbon dioxide with aqueous solutions of l-Arginine, Glycine & Sarcosine using the stopped flow technique
(
Elsevier
, 2017 , Article)
The use of amino acids as potential solvents for carbon dioxide (CO2) capture has been considered by a number of researchers. However, very little is known about the kinetics and mechanism of amino acids-CO2 reactions. In ...