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Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals

Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; ... more authors ... less authors ( MDPI , 2020 , Article)

Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ...

Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

Younes, Nadin; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Younes, Salma; Al-Jamal, Ola; ... more authors ... less authors ( MDPI , 2020 , Article)

The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, ...

Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

Laith J., Abu-Raddad; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; ... more authors ... less authors ( Elsevier , 2021 , Article)

We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or ...

Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality

Wehbe, Zena; Hammoud, Safaa Hisham; Yassine, Hadi M; Fardoun, Manal; El-Yazbi, Ahmed F; ... more authors ... less authors ( Frontiers Media , 2021 , Article)

Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...

SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar.

Al-Thani, Mohamed H; Farag, Elmoubasher; Bertollini, Roberto; Al Romaihi, Hamad Eid; Abdeen, Sami; ... more authors ... less authors ( Oxford University Press , 2021 , Article)

Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study ...

Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.

Ismail, Ahmed; Shurrab, Farah M; Al-Jighefee, Hadeel T; Al-Sadeq, Duaa W; Qotba, Hamda; ... more authors ... less authors ( IMR , 2021 , Article)

Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ...

Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience

Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; ... more authors ... less authors ( International Society of Global Health , 2022 , Article)

Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ...