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AdvisorAdawi, Karam I. I.
AuthorABU-EL-RUZ, RASHA
Available date2022-06-15T09:10:16Z
Publication Date06-2022
URIhttp://hdl.handle.net/10576/32111
AbstractBackground: Chlamydia trachomatis (CT) is a Sexually Transmitted Disease (STD); it leads to health complications and infertility if not treated. Aim: To provide a comprehensive epidemiological assessment of CT in Latin America and the Caribbean (LAC). Methods: This study followed Cochran and PRISMA guidelines. We conducted the search in PubMed, Embase, and LILACS databases. We estimated the pooled-mean CT prevalence using random-effects meta-analyses. We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. Urogenital CT prevalence appears to decrease with age, to be higher in women compared to men, and to increase by 1% yearly. Anorectal CT appears to be higher in men compared to women but shows no temporal trend. Discussion: Urogenital CT prevalence among general populations is higher than that in other world regions. Conclusion: LAC is burdened by CT infection. Public health response in LAC region is required to effectively tackle CT infection.
Languageen
SubjectChlamydia trachomatis
Latin America and Caribbean
Sexually Transmitted Diseases
TitleEPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS
TypeMaster Thesis
DepartmentPublic Health
dc.accessType Open Access


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