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المؤلفAllehdan, Sabika
المؤلفBassil, Maya
المؤلفAlatrash, Razan M.
المؤلفAl-Jaberi, Tareq
المؤلفHushki, Ahmad
المؤلفRayyan, Yaser
المؤلفDahoud, Mahammad
المؤلفAbu-Eiteen, Khaled
المؤلفTayyem, Reema F.
تاريخ الإتاحة2022-06-20T09:31:29Z
تاريخ النشر2022-06-01
اسم المنشورNutrients
المعرّفhttp://dx.doi.org/10.3390/nu14122373
الاقتباسAllehdan, S.; Bassil, M.; Alatrash, R.M.; Al-Jaberi, T.; Hushki, A.; Rayyan, Y.; Dahoud, M.; Abu-EIteen, K.; Tayyem, R.F. Macronutrients Intake and Risk of Stomach Cancer: Findings from Case-Control Study. Nutrients 2022, 14, 2373. https://doi.org/10.3390/nu14122373
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85131542402&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/32144
الملخصStudies on the association between gastric cancer (GC) and the intake of nutrients in Jordan are very limited, while findings from other reports on the intake of energy and macronutrients are controversial. This study aimed to examine the associations between intake of energy and macronutrients and the risk of GC in a Jordanian population. A case-control study was carried out between March 2015 and August 2018 in four major hospitals, including an oncology center in Jordan. Study participants were 173 cases with incident and histologically confirmed GC and 314 frequency-matched controls. Interview-based questionnaires were used to obtain the study’s information. Data on nutrient intake were collected using a validated Arabic food-frequency questionnaire (FFQ). Odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were calculated through multinomial logistic regression and adjusted for potential confounders, including age, marital status, education, body mass index (BMI), smoking, period of smoking, family history of gastric cancer, history of gastric ulcer, and physical activity. Intakes of total fat, saturated fat, monounsaturated fat, polyunsaturated fat, cholesterol, trans-fat, and omega-6 fatty acids were significantly associated with increased risk of GC. The ORs for the highest versus the lowest tertiles were 6.47 (95% Cl: 3.29–12.77), 2.97 (95% CI: 1.58–5.58), 6.84 (95% CI: 3.46–13.52), 6.19 (95% CI: 3.15–12.17), 3.05 (95% CI: 1.58–5.88), 8.11 (95% CI: 4.20–15.69), and 2.74 (95% CI: 1.47–5.09), respectively. No significant association was found for energy, protein, carbohydrate, sugar, fibers, and omega-3 fatty acids. The findings of this study suggest that high intake of selected types of fats was associated with an increased risk of GC.
راعي المشروعThis research was funded by the Hashemite University [1403938/10/13/16AM].
اللغةen
الناشرMDPI
الموضوعcase-control study
fat
gastric cancer
macronutrients
العنوانMacronutrients Intake and Risk of Stomach Cancer: Findings from Case-Control Study
النوعArticle
رقم العدد12
رقم المجلد14
ESSN2072-6643
dc.accessType Open Access


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